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Motion sickness is a very common disturbance of the inner ear that
is caused by repeated motion such as from the swell of the sea, the
movement of a car, the motion of a plane in turbulent air, etc.
Most medications for motion sickness need to be taken at least 30
minutes prior exposure to the activity that can cause the problem.
The Mouth Dissolving Films (MDF) are rapidly dissolving dosage
forms which when placed in the mouth release the drug immediately.
This solution of drug in saliva when swallowed will get rapidly
absorbed in the GIT producing a rapid onset of action. These dosage
forms would be preferred by pediatric and geriatric patients since
these are not associated with fear of choking.Meclizine HCl was
used as anti-emetic drug, mainly because of it diminishes
vestibular stimulation and depresses labyrinthine function. An
action on the medullary chemoreceptive trigger zone may also be
involved in the antiemetic effect. Other reason is that it has less
side effect compare to other anti-emetic drugs.
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