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In this study, the numerical phenetic method was applied on
Coccinella undecimpunctata Linnaeus and its 13 aberrations. These
aberrations were collected from 10 localities from Lower and Upper
Egypt. The morphometric measures were used to obtain a phenogram
representative of phenetic similarities and affinities among the
all morphs. RAPD fingerprint profiles were generated by using five
random primers on genomic DNA to characterize all the aberrations
and to determine their phenetic relationships as well as to
investigate the molecular markers among the aberrations genotypes.
The genetic variability of the populations of one morph(ab.1),
collected from the different 10 localities, was analyzed to verify
the identity of these populations in Egypt, to quantify the genetic
diversity within the population and to differentiate among the
populations.
In this study, the physiological and molecular effects of two
cholesterol lowering agents, synthetic statin (atorvastatin) and
natural statin (simvastatin) on diabetic and hypercholesterolemic
adult male Wistar albino rats (Rattus norvegicus)at two doses, 10
and 40 mg/kg, for 8 weeks was investigated. Other physiological
parameters were evaluated under this investigation, like: glucose,
urea, uric acid, creatinine, total protein, albumin, globulin, A/G
ratio, total, direct and indirect billirubin) To assess the
beneficial effect of the drugs on liver genomic DNA, the (RE)
analysis with 5 restriction endonucleases manifested variations in
DNA digestion patterns in diabetic and hypercholesterolemic rats
treated with atorvastatin and simavstatin. Such variation reflects
and clarifies a restoration and repairing effect of statin on rat
liver DNA in diabetic and hypercholesterolemic rats.
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