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This book offers a timely and comprehensive review of essential
research on Peste des Petits Ruminants Virus (PPRV), ranging from
its historical distribution, molecular epidemiology, genome
structure, viral proteins, immunity, viral pathogenesis, clinical
and molecular diagnosis to advances in vaccine developments and
future challenges. PPRV, a Rinderpest-like virus, is the causative
agent of one of the most rapidly emerging viral diseases among
domestic small ruminants, and the host spectrum has now been
expanded to wild small ruminants and camels. With the global
eradication of the first livestock disease, Rinderpest, attention
is now turning to repeating the procedure for PPR. Each of the
book's 13 chapters is dedicated to a specific topic, providing
up-to-date literature and discussions by renowned scientists who
have made seminal contributions in their respective fields of
expertise. Special emphasis has been placed on the analysis of
different global efforts to eradicate PPR. This book offers a
valuable reference source for virologists, field veterinarians,
infection and molecular biologists, immunologists, scientists in
related fields and veterinary school libraries.
This book offers a timely and comprehensive review of essential
research on Peste des Petits Ruminants Virus (PPRV), ranging from
its historical distribution, molecular epidemiology, genome
structure, viral proteins, immunity, viral pathogenesis, clinical
and molecular diagnosis to advances in vaccine developments and
future challenges. PPRV, a Rinderpest-like virus, is the causative
agent of one of the most rapidly emerging viral diseases among
domestic small ruminants, and the host spectrum has now been
expanded to wild small ruminants and camels. With the global
eradication of the first livestock disease, Rinderpest, attention
is now turning to repeating the procedure for PPR. Each of the
book's 13 chapters is dedicated to a specific topic, providing
up-to-date literature and discussions by renowned scientists who
have made seminal contributions in their respective fields of
expertise. Special emphasis has been placed on the analysis of
different global efforts to eradicate PPR. This book offers a
valuable reference source for virologists, field veterinarians,
infection and molecular biologists, immunologists, scientists in
related fields and veterinary school libraries.
Peste de Petits Ruminants (PPR) is a highly contagious viral
disease of domestic and wild small ruminants that can significantly
affect economies. The authors are experts in the field and provide
an up-to-date and comprehensive review covering all aspects of the
disease. The book is divided into seven chapters highlighting
genome organization, virus replication and the determinants of
virulence, pathophysiology and clinical disease, immunology and
immunopathogenesis, epidemiology, diagnostic assays and vaccines,
and the challenges concerning global eradication. It is an
invaluable reference work, presenting the latest information for
virologists, microbiologists, immunologists, veterinarians, and
scientists working in PPR research.
The Mononegavirales is an order of viruses affecting large, small
and marine animals and is responsible for diseases including
Rinderpest, Rabies and Ebola. This book discusses the epidemiology
and control of Mononegaviruses that pose a significant threat to
animals in terms of severity and epidemiological risk. The book
also addresses viruses with zoonotic potential, and many that can
be used as models in the study of infectious disease. With its
comprehensive coverage, each chapter is dedicated to a different
disease and has been authored by renowned scientists who have made
seminal contributions to the field. This prestige reference work is
arranged over two volumes: volume 1 pathobiology and molecular
diagnosis, and volume 2 molecular epidemiology and control. This
broad ranging text covers mononegaviral diseases of livestock,
horses, dogs and cats as well as rodents, primates, fish and marine
mammals, and will be a valuable reference source for virologists,
field veterinarians, infection and molecular biologists as well as
immunologists and animal scientists.
Mononegavirales is a family of viruses affecting large, small and
marine animals. Discussing the pathology and laboratory diagnosis
of important viruses, this book covers those that cause a
significant threat to animals in terms of their severity and
epidemiological risk, as well as those which are used as models in
the study of infectious disease. Also including viruses with
zoonotic potential, this book reviews the literature for
Rhinderpest, Rabies, Ebola and more.
PPR is a contagious disease of small ruminants and causes enormous
economical losses due to its acuteness and misdiagnoses. The
diagnostic tools are not readily available in all diagnostic
laboratories especially in developing nations, where disease is
endemic. Therefore, it is need to establish reliable, sensitive and
affordable diagnostic tools, which will be promptly accessible at
low cost, independent of laboratory type. Until this
accomplishment, the dire need of time is to evaluate the different
serological tests and to perform a parallel comparison with the aim
to adapt these tests as a diagnostic method, which helps to
diagnose and control PPR in developing nations. This reasons the
primary objective of this book. This book would provide information
about different assays by perform a parallel comparison to that of
reference standards. This validation would guide the local
authorities to choose the best-suited assay for the diagnosis of
PPRV in the region. The book begins with a general introduction of
the PPR virus and disease, handling practical issues, and
step-by-step guide for each procedure. As a rational, a case study
for each technique is presented.
This book was an effort for wheat improvement under salinity
stress.One hundred and eighty seven wheat genotypes were evaluated
at germination, vegetative and maturity stage under 200, 250 and
300 mM NaCl stress.Various morphological and molecular markers were
utilized to screen salt tolerant cultivars. Vegetative stage was
found to be most salinity sensitive stage. Therefore, genotypes
should be evaluated at this stage by using molecular,
physiological, morphological and biochemical approaches. More than
10 SSR markers were found to be linked with salinity
tolerance.Heritability estimates and gene action studies revealed
that potential for improving salinity tolerance in wheat does
exist.
This book gives comprehensive review of the literature regarding
PPRV and provides fundamental diagnostic tools that can be employed
for the efficient diagnosis and control of PPRV. In this regard,
two diagnostic tools, agar gel immunodiffusion test and
precipitinogen inhibition test, were compared and evaluated in
parallel to immunocapture ELISA. All these techniques were
comprehensively discussed and practical aspects specially
emphasized. Furthermore, the governmental livestock farms were
reported to be seropositive for PPRV and are analyzed in detail.
This highlights the importance of PPRV and it is the need of the
time to attract the attention of controlling authorities to this
devastating disease. In short, this book will be helpful to all the
scientists involved in the diagnostic application of serological
tests for PPRV.
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