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The aim of study was to evaluate plasma antioxidant status, protein
content, glycemic level, lipid profiles and lipid peroxidation
products in type 2 diabetic patients and any effect of gender on
these biochemical parameters. Plasma total cholesterol (TC),
triglycerides (TG), low density lipoproteins (LDL) and high density
lipoproteins (HDL) levels, Antioxidants i.e. superoxide dismutase
(SOD, EC 1.15.1.1), catalase (CAT, EC 1.11.1.6) peroxidase (POD, EC
1.11.1.7) and plasma Malondialdehyde (MDA) content were
significantly higher in diabetic patients. Elevated glucose level,
lipid profiles and peroxidation products indicating oxidative
stress damage in diabetic patients. Antioxidants like SOD and CAT
were enhanced in response to oxidative stress by hyperglycemia and
thus to detoxify the excessive reactive oxygen species (ROS).
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