Danny Glover and Martin Short star in this comedy directed by Nadia Tass. After Valerie (Sheila Kelley), the unlucky daughter of powerful businessman Highsmith (Sam Wanamaker), disappears on the first day of her Mexican holiday, Detective Raymond Campanella (Glover) is recruited to track her down. Unable to find her, Highsmith employs the services of the equally unlucky Eugene Proctor (Short) to assist Campanella, hoping his bad luck will somehow help them in their investigation. Stumbling from one mishap to another, the pair must overcome a number of unlikely obstacles as they do all they can to retrace Valerie's steps through the streets of Acapulco.

Drama in which the parents of two severely ill children find themselves caught up in a romance. Marissa (Jacinda Barrett) appears to have the perfect life. She is beautiful, rich and has a charming husband David (Richard Roxburgh) and a son, Jack (Tom Russell). However, when Jack is diagnosed as suffering from cancer, things begin to fall apart. David's confession that he has had a series of affairs causes disruption to the marriage, yet if he has fathered an illegitimate child this could be the source of the bone marrow transplant Jack's life depends on. In the midst of all this, Marissa meets Connor (James Nesbitt), an Irish father who also has a sick son. Marissa and Connor bond over their children's bedsides, but can a burgeoning romance survive the trauma of a children's cancer ward?