In consultation with Consulting Editor Dr. William Rayburn, Dr. Santor and Dr. Kravitz have put together an issue that comprehensively covers age-related changes in women. Their authors, from well-respected institutions, have contributed review articles on the following topics: Declining fertility with reproductive aging: How to protect your patient's fertility by knowing the milestones; Onset of the transition into menopause: What are the earliest signs; Menstrual cycle changes as women approach the final menses: What matters; Menstrual cycle hormone changes and how they may link to symptoms; Symptom progression across the transition: Not all women are created equal; Cardiovascular implications of vasomotor symptoms and the menopausal transition; Depression and perimenopause :Hormones, genetics and environmental determinants of disease; Sleep, health, and metabolism: Food for thought; Bone health during the menopausal transition and beyond; Sexuality in midlife and beyond; Physical function -moving and aging; Genitourinary changes with aging; and Cognitive changes with reproductive aging, perimenopause, and menopause. Readers will come away with the latest clinical information they need to treat these patients and improve outcomes.

This issue of Endocrinology and Metabolism Clinics, edited by Drs. Nanette Santoro and Lubna Pal, is devoted to Postmenopausal Endocrinology. Articles in this issue include: Endocrinology of Menopause; Menopausal Symptoms; Bone Health and Osteoporosis; Surgical Menopause; Premature Menopause; Cardiovascular Changes; MHT: Current Considerations; Breast Cancer and Hormones; Other Cancers and Menopause; CAM for Menopausal Symptoms; Menopause and Sexuality; and Menopause and Metabolism.

Perimenopause has not been covered in the Obstetrics and Gynecology Clinics for over 10 years.? This timely issue includes articles on BMI and its influence, Androgens, Cognition and Menopause, and Sexual Activity/Quality of Life.