A dazzlingly erudite synthesis of history, philosophy, anthropology, genetics, sociology, economics, epidemiology, statistics, and more (Frank Bruni, The New York Times), Blueprint shows why evolution has placed us on a humane path -- and how we are united by our common humanity. For too long, scientists have focused on the dark side of our biological heritage: our capacity for aggression, cruelty, prejudice, and self-interest. But natural selection has given us a suite of beneficial social features, including our capacity for love, friendship, cooperation, and learning. Beneath all of our inventions -- our tools, farms, machines, cities, nations -- we carry with us innate proclivities to make a good society. In Blueprint, Nicholas A. Christakis introduces the compelling idea that our genes affect not only our bodies and behaviors, but also the ways in which we make societies, ones that are surprisingly similar worldwide. With many vivid examples -- including diverse historical and contemporary cultures, communities formed in the wake of shipwrecks, commune dwellers seeking utopia, online groups thrown together by design or involving artificially intelligent bots, and even the tender and complex social arrangements of elephants and dolphins that so resemble our own -- Christakis shows that, despite a human history replete with violence, we cannot escape our social blueprint for goodness. In a world of increasing political and economic polarization, it's tempting to ignore the positive role of our evolutionary past. But by exploring the ancient roots of goodness in civilization, Blueprint shows that our genes have shaped societies for our welfare and that, in a feedback loop stretching back many thousands of years, societies are still shaping our genes today.

Renowned scientists Christakis and Fowler present compelling evidence for our profound influence on one another's tastes, health, wealth, happiness, beliefs, even weight, as they explain how social networks form and how they operate.

This groundbreaking book explains prognosis from the perspective of doctors, examining why physicians are reluctant to predict the future, how doctors use prognosis, the symbolism it contains, and the emotional difficulties it involves. Drawing on his experiences as a doctor and sociologist, Nicholas Christakis interviewed scores of physicians and searched dozens of medical textbooks and medical school curricula for discussions of prognosis in an attempt to get to the core of this nebulous medical issue that, despite its importance, is only partially understood and rarely discussed.
"Highly recommended for everyone from patients wrestling with their personal prognosis to any medical practitioner touched by this bioethical dilemma."--"Library Journal, " starred review
" T]he first full general discussion of prognosis ever written. . . . A] manifesto for a form of prognosis that's equal parts prediction-an assessment of likely outcomes based on statistical averages-and prophecy, an intuition of what lies ahead."--Jeff Sharlet, "Chicago Reader"
" S]ophisticated, extraordinarily well supported, and compelling. . . . Christakis] argues forcefully that the profession must take responsibility for the current widespread avoidance of prognosis and change the present culture. This prophet is one whose advice we would do well to heed."--James Tulsky, M.D., "New England Journal of Medicine"

Apollo's Arrow offers a riveting account of the impact of the coronavirus pandemic as it swept through American society in 2020, and of how the recovery will unfold in the coming years. Drawing on momentous (yet dimly remembered) historical epidemics, contemporary analyses, and cutting-edge research from a range of scientific disciplines, bestselling author, physician, sociologist, and public health expert Nicholas A. Christakis explores what it means to live in a time of plague-an experience that is paradoxically uncommon to the vast majority of humans who are alive, yet deeply fundamental to our species. Unleashing new divisions in our society as well as opportunities for cooperation, this 21st-century pandemic has upended our lives in ways that will test, but not vanquish, our already frayed collective culture. Featuring new, provocative arguments and vivid examples ranging across medicine, history, sociology, epidemiology, data science, and genetics, Apollo's Arrow envisions what happens when the great force of a deadly germ meets the enduring reality of our evolved social nature.

Drawing on advances in social science, evolutionary biology, genetics, neuroscience and network science, Blueprint shows how and why evolution has placed us on a humane path -- and how we are united by our common humanity. For too long, scientists have focused on the dark side of our biological heritage: our capacity for aggression, cruelty, prejudice, and self-interest. But natural selection has given us a suite of beneficial social features, including our capacity for love, friendship, cooperation, and learning. Beneath all our inventions - our tools, farms, machines, cities, nations - we carry with us innate proclivities to make a good society. In Blueprint, Nicholas A. Christakis introduces the compelling idea that our genes affect not only our bodies and behaviors, but also the ways in which we make societies, ones that are surprisingly similar worldwide. With many vivid examples -- including diverse historical and contemporary cultures, communities formed in the wake of shipwrecks, commune dwellers seeking utopia, online groups thrown together by design or involving artificially intelligent bots and even the tender and complex social arrangements of elephants and dolphins that so resemble our own - Christakis shows that, despite a human history replete with violence, we cannot escape our social blueprint for goodness. In a world of increasing political and economic polarisation, it's tempting to ignore the positive role of our evolutionary past. But by exploring the ancient roots of goodness in civilisation, Blueprint shows that our genes have shaped societies for our welfare and that, in a feedback loop stretching back many thousands of years, societies have shaped and are still shaping, our genes today.

APOLLO'S ARROW offers a riveting account of the impact of the coronavirus pandemic on American society as it unfolded in 2020, and on how the recovery will unfold in the coming years. Drawing on a combination of fascinating case studies and cutting-edge research from a range of scientific disciplines, bestselling author, physician, and sociologist Nicholas Christakis explores what it means to live in a time of plague -- an experience that is paradoxically uncommon to the vast majority of humans who are alive, yet deeply fundamental to our species as a whole. Unleashing new divisions in our society and new opportunities for cooperation, this 21st century pandemic has upended our society in ways that will test, but not vanquish, our already frayed culture's capacity to endure and thrive. Featuring many novel, provocative arguments and vivid examples ranging across medicine, history, sociology, epidemiology, data science, and genetics, APOLLO'S ARROW envisions what happens when the great force of a deadly germ meets the enduring reality of our evolved social nature.

Predicting survival and other outcomes is increasingly being recognized as an important skill for palliative care doctors and nurses, oncologists, and other healthcare professionals who treat patients with advanced cancer. Accurate prognosis is essential if we are to offer quality of care and 'a good death', as well as to aid decision-making. There is much prognostic information available that is scattered throughout the palliative care and oncological literature but this is the first time it has been gathered systematically in one place.
Glare and Christakis, leaders in the field of prognosis, bring together a team of international contributors from across the fields of palliative care and oncology. This comprehensive but practical guide begins with the principles of prognostication, including formulating the prediction and then communicating it. Topics such as statistical issues, evidence-based medicine, and the ethics of prognostication are also covered. The second section addresses prognostication in 15 specific cancer sites once they have reached the advanced stage, following a standard template for consistency and easy access to the key information. The third section deals with prognostication in patients with a variety of common clinical conditions at the end of life, such as bowel obstruction, hypercalcaemia, and brain metastases. In addition, survival curves are provided within each chapter, palliative care conditions are examined for the first time, and a summary table of long and short term prognosis ensures this book remains practical.