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This book outlines the use of supramolecules as different
pharmaceutical drugs. Supramolecular chemistry in pharmaceutical
sciences is quite a young and rapidly developing field.
Supramolecular assemblies might offer an alternative for existing
pharmaceutical formulations, as they facilitate the improvement of
physicochemical and pharmacological properties i.e., higher
bioavailability, better biocompatibility and drug-targeting, fewer
multidrug-resistances. This book offers an overview of the recent
advances in supramolecular structures and discusses the future
aspects and challenges related to the development of these
molecules, providing also a perspective on how to overcome these
issues. Divided into 13 chapters contributed by experts in their
field, the book provides a deeper understanding of intermolecular
forces playing pivotal roles in mediating the interactions between
chemical molecules and biological systems by focusing on different
applications of supramolecular compounds. In this book, readers
will find valuable insights into the preparation of supramolecules
and the latest research and development trends of supramolecules as
anticancer drugs, including liquid-crystalline supramolecular
assemblies, and as antimicrobial, antiviral, anti-inflammatory and
cardiovascular drugs. Particular attention is given to the
application of supramolecules in the fields of biomedicine,
bioimaging, and vaccine development. Given its breadth, this book
will appeal to a wide readership from researchers and students
interested in these fields to professionals in the pharma industry.
Covers all aspects related with Metal Organic Frameworks (MOF),
including characterization, modification, applications, and
associated challenges Illustrates designing and synthetic
strategies for MOFs Describes MOFs for gas adsorption, separation
and purification, and their role in heterogeneous catalysis Covers
of sensing of different types of noxious substances in the aqueous
environment Includes concepts of molecular magnetism, tunable
magnetic properties and future aspects
Advancement of Phenolic Acids in Drug Discovery: Fundamental and
Applications offers comprehensive coverage of the ADMET profiles of
phenolic acids, their extraction method and prospects for drug
design and development. Chapters overview phenolic acids and their
characterization, discuss the role of phenolic acids in plant
systems, present sources and detailed extraction methods of
phenolic acids, and cover phenolic acid mechanisms of action as it
relates to several key diseases and health conditions, including
their role as antioxidant agents, anti-inflammatory and analgesic
drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs,
diabetes and metabolic dysfunctions, neurological disorders,
cardiovascular diseases. The book’s final chapters cover
nanoscience aspects of phenolic acids, biomedical applications, and
concludes with challenges and opportunities presented by phenolic
acids. This is the ideal reference for researchers in the fields of
drug development, both in academia and corporate settings.
Researchers of related areas like food science and medicinal
chemistry will also benefit from this in-depth profiling of
therapeutical properties of phenolic acids.
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