V knige predstavleny dannye ob epidemiologicheskikh, klinicheskikh, funktsional'nykh i metabolicheskikh osobennostyakh arterial'noy gipertenzii s soputstvuyushchey patologiey zhelchevydelitel'noy sistemy u prishlogo naseleniya na Severe. Osoboe vnimanie udeleno rasprostranennosti arterial'noy gipertenzii sochetannoy s zabolevaniyami zhelchevydelitel'noy sistemy u prishlogo naseleniya v zavisimosti ot srokov prozhivaniya na Severe. Pokazano, chto v otlichie ot izolirovannoy arterial'noy gipertenzii pri sochetannoy patologii u bol'nykh klinicheski bolee vyrazheno proyavlyayutsya simptomy povyshennogo tonusa parasimpaticheskogo otdela vegetativnoy nervnoy sistemy. S uvelicheniem dlitel'nosti prozhivaniya na Severe u patsientov s sochetannoy patologiey chashche otmechayutsya oslozhneniya zabolevaniy, takie kak: ostryy kal'kuleznyy kholetsistit, ostryy pankreatit. V gruppe bol'nykh s sochetannymi nozologiyami proiskhodit izmenenie gormonal'nogo i metabolicheskogo statusa organizma v zavisimosti ot dlitel'nosti prozhivaniya na Severe. U bol'nykh s sochetannoy patologiey, prozhivayushchikh na Severe, opredelyaetsya fazovaya dinamika izmeneniya funktsional'nogo sostoyaniya vegetativnoy nervnoy sistemy po dannym spektral'nogo analiza serdechnogo ritma.

V knige predstavleny dannye o kliniko-funktsional'nykh i patogeneticheskikh osobennostyakh arterial'noy gipertenzii u bol'nykh s razlichnym sutochnym profilem arterial'nogo davleniya, prozhivayushchikh v usloviyakh Tyumenskogo severa (g. Megion) i Respubliki Sakha (Yakutiya). Osoboe vnimanie udeleno vzaimosvyazyam sutochnykh pokazateley gemodinamiki u bol'nykh arterial'noy gipertenziey so stepen'yu progressirovaniya gipertrofii miokarda levogo zheludochka, giperkholesterinemiey, vyyavlyaemymi narusheniyami uglevodnogo obmena. Privedeny dannye mnogofaktornogo analiza vozmozhnogo vliyaniya osobennostey geofizicheskikh faktorov Severa na funktsional'noe sostoyanie serdechno-sosudistoy sistemy u bol'nykh arterial'noy gipertenziey. Predstavleny rekomendatsii po primeneniyu sutochnogo monitorirovaniya arterial'nogo davleniya v diagnostike kardiovaskulyarnoy patologii u prishlykh zhiteley Severa, ucheta etikh dannykh pri professional'nom otbore dlya raboty v usloviyakh severa Sibirskogo regiona. Monografiya predstavlyaet interes dlya terapevtov, kardiologov, ekologov, sotrudnikov nauchno-issledovatel'skikh institutov, studentov meditsinskikh i biologicheskikh vuzov.