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Peptide and Peptidomimetic Therapeutics: From Bench to Beside
offers applied, evidence-based instruction on developing and
applying peptide therapeutics in disease treatment, driving drug
discovery, and improving patient care. Here, researchers,
clinicians and students will find tools to harness the full power
of peptides and peptidomimetics and improve bioavailability,
stability, efficiency and selectivity of new therapeutics and their
application in treatment plans. More than 20 leaders in the field
share their approaches for identifying and advancing peptide and
peptidomimetic therapeutics. Topics examined run from "bench to
bedside," beginning with fundamental peptide science,
protein-protein interactions and peptide synthesis. Later chapters
examine modes for peptide drug delivery, including cell penetration
peptide and peptidomimetic delivery, as well as the targeting of
specific disease types, peptide therapeutics as applied to
infectious disease, cancer, metabolic disorders, neurodegenerative
disorders, and skin disorders, and antiparasitic and
immunosuppressive peptidomimetics.
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