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Medicinal plants are important source to be explored for the
discovery and development of newer, safer and effective drug
candidates. In medicinal plants research, bioactivity guided
phytochemical research can be considered as a rational approach.
The ethanopharmacological investigations of the study plant
Schoenoplectus grossus was carried out for the first time ever in
research lab by Professor Dr. Rahman's research group. The powdered
root of this plant was extracted with methanol and fractioned by
modified Kupchan partitioning method to provide petroleum ether,
carbon tetrachloride, dichloromethane, and ethyl acetate soluble
fractions. All fractions and methanol extract were investigated for
pharmacological activities on animal model. The analgesic,
antipyretic, anti-inflammatory, antihelmintic, and antidiarrheal
effects were analyzed on dose dependent manner by comparing with
standard reference drug. The extract was also screened out for
cytotoxic, antioxidant, and thrombolytic activity by in vitro
methods.
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