This edited volume summarizes recent findings of leading researchers investigating the brain systems that underlie memory. The book reviews recent progress in understanding forms of memory in animals and humans and the interaction of cortical and subcortical systems in the regulation of memory. Special emphasis is given to the development of neural network models that attempt to link cells to systems in the representation of memory. The book will be an invaluable source for cognitive psychologists, neuroscientists, and students interested in this active and exciting area of research.

This book brings together an internationally respected group of researchers for the purpose of examining neuroplasticity, a topic of immense current interest in psychology, neuroscience, neuropsychology, and clinical neurology. The chapters represent state-of-the-art work on neuroplasticity at all levels: behavioral, neural, and molecular. They describe recent work on memory ranging from cellular morphological studies in invertebrates to research on the human brain made possible by new advances in neuroimaging technology. The book begins with an introductory chapter that considers the psychology of memory at the global, structural level. The remainder of the volume is divided into three related parts. The first focuses on recent approaches, which are based in part on new technology, that aim to measure and describe activity in relatively large populations of neurons. The second focuses on memory at the level of brain systems. One major theme to emerge from work at this level is that memory is composed of multiple, separable components that can be identified with specific anatomical structures and connections. The third part of the book focuses on molecular and cellular studies that show how individual neurons and their synapses behave in a history-dependent manner. This research concerns both brief changes in synaptic plasticity as well as more lasting changes in connectivity, which depend on altered gene expression and morphological growth and change. Altogether, the chapters provide a rich summary of the breadth and excitement of contemporary research on the biology of memory.

We are approaching the end of the first century of attempts to discover how the brain enables us to acquire, retain, and use information based on experience. The past several decades especially have witnessed an ever accelerating pace of research. This increase is due in large part to the development of new techniques for the analysis of brain and behavior. But, to a greater extent, these advances have been fueled by some seminal findings and the accumulation of knowledge based on systematic inquiry in many laboratories around the world. This important volume, authored by internationally renowned leaders in the field, is a progress report on this burgeoning work. What processes underlie the formation of new memories? What determines their strength? Where are the changes underlying memory located? In judging recent progress, this book looks at what we have learned about each of these questions. Furthermore, the contributors look at how these questions are rephrased and refined by new findings, hypotheses, and theories. Topics include: emotion and memory, aging and memory, plasticity of the cerebral cortex, and synaptic connectivity and memory. This book will be welcomed by neuroscientists, cognitive psychologists, and cognitive scientists.