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Showing 1 - 25 of
37 matches in All Departments
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Reviews of Physiology, Biochemistry and Pharmacology, 88 (English, German, Paperback, Softcover reprint of the original 1st ed. 1981)
R.H. Adrian, H. Zur Hausen, E. Helmreich, H Holzer, R Jung, …
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R3,026
Discovery Miles 30 260
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Ships in 10 - 15 working days
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Reviews of Physiology, Biochemistry and Pharmacology, 87 (English, German, Paperback, Softcover reprint of the original 1st ed. 1980)
R.H. Adrian, H. Zur Hausen, E. Helmreich, H Holzer, R Jung, …
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R1,592
Discovery Miles 15 920
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Ships in 10 - 15 working days
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Between 1950 and 1960, remarkable advances were made in the
develQpment Qf antihypertensive drugs, but since then, prQgress has
been less rapid. This dQes nQt mean that no. new drugs have been
intrQduced: Qn the cQntrary, their number has increased sharply;
but since the advent Qf the beta-adrenergic blQckers no. new
pharmacQdynamic principle has been discQvered that CQuid be applied
widely as an antihypertensive. This has nQt been fQr want Qf
effQrts, because many attempts have been made to. find new ways and
means Qf influencing blQQd- pressure regulatiQn Qr the mechanisms
invQlved in the pathQgenesis Qf hypertensiQn. HQwever, the results
Qf these endeavQrs have mQstly been disapPQinting. Even thQugh high
blQQd pressure can be treated mQre satisfactQrily tQday than many
Qther diseases, the success achieved in cQmbating Qne Qf man's mQst
frequent ailments shQuld nQt induce cQmplacency, but rather
stimulate research tQwards further imprQvements. The present
standstill affQrds an QPPQrtunity to. review the field Qf antihy-
pertensive agents, fQr it is unlikely that fundamentally new drugs
will appear in the near future. AlthQugh greater knQwledge has been
gained Qf the mechanisms Qf blQQd-pressure regulatiQn and Qf the
pathQgenesis Qf hypertensiQn, these ad- vances have had no. direct
cQnsequences in the search fQr new therapeutics.
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