Asthma is a chronic illness involving the respiratory system in which the airway constricts, becomes inflamed, and is lined with excessive amounts of mucous, often in response to one or more trigger. It is becoming increasingly evident that the cause of the changes in asthma are multifactorial, including contribution from allergen exposure, hygiene and lifestyle changes mainly of diet and physical activity and their product (obesity). We aim to study the clinical and functional changes in asthmatic children after a schedualized training program (walking, swimming, cycling, running and gymnastic) and to evaluate the efficacy of physical activity on both asthma symptoms and pulmonary functions, aiming to modify the asthmatic children's life style. We found clear evidence that Pulmonary Rehabilitation programs that include individually prescribed but generic physical exercise training are capable of improving functional exercise capacity and health-related quality of life and are cost effective, so it should be applied on a larger scale among asthmatic children hospitals, various allergy clinics and even at school if possible, to improve their health outcome and quality of life.