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Parkinson's disease is the second most common neurodegenerative disorder in the world after Alzheimer's disease. Thanks to the pioneering works of Arvid Carlson in the 20th century identifying dopamine as the main neurochemical agent involved in Parkinson's disease's onset and progress, our understanding of the neuropathology has increased. The elaboration of L-Dopa as the first pharmacological treatment approach has brought new hope for curing or at least slowing the neurodegenerative progress and the decline of motor and cognitive functions in Parkinson's disease patients. To date, imaging techniques along with genetic and biochemical tools have allowed scientists and clinicians to predict and diagnose the disease several years prior to the motor disorder's appearance. Experimental and Clinical Evidence of the Neuropathology of Parkinson's Disease sheds light on the history of Parkinson's disease as well as the recent literature on the epidemiological data worldwide including the prevalence of the disease, the morbimortality rates, and the sex dimorphism and aging components. It addresses the current neuropathological evidence of Parkinson's disease, including the latest discoveries in terms of neuropathology and treatments available or under clinical trials with the efficacy and limitations of each. Covering topics such as epidemiology, stem cells, and neuropathology, this premier reference source is an excellent resource for clinicians, physicians, epidemiologists, neuroscientists, microbiologists, biochemists, pharmacologists, toxicologists, medical professionals, nurses, medical students and educators, librarians, researchers, and academicians.
According to the World Health Organization (WHO), coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus (SARS-Cov2), which may cause mild to moderate respiratory complications in most infected people. Older people and those with chronic and/or acute illnesses may present serious complications. Underlying mechanisms of the cellular responses to the virus are not fully revealed; therefore, understanding the pathophysiology of COVID-19 is crucial to provide efficient data to define the appropriate and effective therapeutic strategies to cure and prevent COVID-19-associated complications. The Handbook of Research on Pathophysiology and Strategies for the Management of COVID-19 summarizes and assembles the published data on COVID-19 and provides an answer to the reader for the mystery of SARS-Cov2's impact on human health through a deep analysis of the current data available in the literature. This book addresses the epidemiology and infectious patterns of the disease and the recent pathophysiological mechanisms of the disease and relationships to the medical history of the patient. Covering topics from the tie between COVID-19 and respiratory disease to vaccination information, this comprehensive reference source is ideal for clinicians, health professionals, pathologists, virologists, researchers, academicians, and medical and PhD students.
The faster climate change affects the globe, the faster individuals will see the negative consequences, which include the decline of general human health. Comprehension of all climate change-related etiologies is essential to understanding the importance of global environmental stability. The Handbook of Research on Global Environmental Changes and Human Health is a collection of innovative research to manage the ensuing and numerous climate and anthropogenic threats to human health. While highlighting topics including government policy, human security, and population sensitivity, this book is ideally designed for environmentalists, policymakers, sociologists, physio pathologists, epidemiologists, and students seeking current research on reducing population sensitivity in terms of health related to the different climatic risks in the changing world.
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