This volume explores the latest techniques and methods used for performing up-to-date glycosylation research. The chapters in this book are organized into four parts. Part One looks at the latest analytical and bioinformatics technologies that enable the characterization of glycosylation complexity. Part Two details the importance of synthetic chemistry and glycoengineering in the fields of bioprocessing and biotherapeutic development. Part Three discusses systems biology and computational technologies used by scientists to analyze glycosylation events in the cell. Part Four focuses on how cellular glycosylation biomarkers can be identified and used to characterize human clinical datasets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Glycosylation: Methods and Protocols is a valuable resource for any scientist or researcher interested in learning more about this exciting and developing field.

This volume explores the latest techniques and methods used for performing up-to-date glycosylation research. The chapters in this book are organized into four parts. Part One looks at the latest analytical and bioinformatics technologies that enable the characterization of glycosylation complexity. Part Two details the importance of synthetic chemistry and glycoengineering in the fields of bioprocessing and biotherapeutic development. Part Three discusses systems biology and computational technologies used by scientists to analyze glycosylation events in the cell. Part Four focuses on how cellular glycosylation biomarkers can be identified and used to characterize human clinical datasets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Glycosylation: Methods and Protocols is a valuable resource for any scientist or researcher interested in learning more about this exciting and developing field.

Designed to support the best-selling third edition of "Medicine at a Glance" (9781405186162), "Medicine at a Glance: Core Cases" contains over 200 cases with self-assessment exercises and answers to aid understanding and test student knowledge.

Following the structure of the main textbook, each chapter presents a number of clinical cases based on the textbook chapter's content. This clinical knowledge is tested by a number of multiple choice self-assessment exercises which can then be applied to practical situations on the ward.

Ideal for medical students and junior doctors, "Medicine at a Glance: Core Cases" Features over 200 case studies and self-assessment exercises based on the best-selling "Medicine at a Glance" (9781405186162)Follows the structure of the main textbook - each chapter presents a number of clinical cases based on the textbook chapter's contentIncludes free access to the online, interactive version featuring feedback and scoring at www.ataglanceseries.com/medicineFor more information on the complete range of "at a Glance" titles, please visit: www.ataglanceseries.com

Chart the dramatic developments in architecture in the late twentieth century with a special selection of critical writing and historical discourse drawn by Michael Spens from the issues of the Architectural Review between 1980 and 1995.

This period saw the magazine play a central role in the re-establishment of modernist theory and critique after the diffusion of the short-lived Post modernist period. History was made through the review articles of such famous authors as Sir John Summerson, P Reyner Banham, William Curtis, Kenneth Frampton, Jean Dethier, Stanford Anderson, Juhani Pallasmaa and Peter Cook. There are also major articles by Peter Davey, the instrumental Editor during this period of historic change, Peter Buchanan, Dan Cruickshank, Peter Blundell-Jones, Martin and others.
The influence of the Review had never been greater than under Davey's own editorship, and arguably the journal played a key formative role during this transition in maintaining and restoring the canon of modern architecture and the development of new ideas. Postmodernism, High-Tech design and New Modernism are all evaluated through theoretical articles and a series of key building critiques. Other topics include Regionalism, The Suburb and Pacific Rim.
Michael Spens, as Editor of the volume, provides a detailed introduction to the contents and describes the background to this achievement, and how it came about that the printed word could again become so influential at a time when criticism had become increasingly ephemeral through media pressures of a new dimension. For any detailed insight into the trends and influences affecting architecture during the past 15 years, this volume will provideacademics, students, and practitioners who have weathered the storm with a compact and essential resource, fully illustrated with carefully selected referential photos and line drawings of the works described.
Twenty major building critiques and twelve theoretical texts provide a thorough review of architectural theory and design
Learn about the key issues in architecture at the end of the twentieth century
Gain a knowledge of the thoughts and beliefs of leading historians and academics which shaped the development of architecture today