In modern drug discovery and development, chemical synthesis is one of the key technologies. For the rapid preparation of new test compounds and drug development candidates, several innovative technologies with great potential have emerged: Microreactor chemistry; Nanotechnology and catalysis research; Microwave-assisted organic synthesis; New developments in solid supported synthesis.

This book covers lectures about the theory, use, scope and limitations of these new technologies in chemical synthesis. It provides a useful overview for scientists in the pharmaceutical industry as well as in academic institutions interested in chemical synthesis for drug discovery and development.

In modern drug discovery and development, chemical synthesis is one of the key technologies. For the rapid preparation of new test compounds and drug development candidates, several innovative technologies with great potential have emerged. This book offers a compact overview of the current status of these technologies and includes many real-life examples from industry and academic institutions.

Thorough coverage of recent developments in the field of solid support oligosaccharide synthesis

Solid-phase synthesis of carbohydrates presents unique challenges to synthetic chemists and currently represents one of the hottest areas of research in bioorganic chemistry. Solid Support Oligosaccharide Synthesis and Combinatorial

Carbohydrate Libraries addresses the exciting expectation that solid-phase assembly of oligosaccharides will have a fundamental impact on the field of glycobiology. This publication details the methodologies currently investigated for the attachment of carbohydrates to beads, synthesis including coupling strategies, and removal of the product from beads.

With chapters written by eminent contributing authors, the material explores different synthetic strategies, glycosylation protocols, the use of solid supports versus soluble polymeric supports, and "on-resin" analytical methods. Tremendous progress in the field has set the stage for Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries to provide a wealth of information on such topics as:

• Specific oligosaccharide structures used in signal transduction processes
• Preparation and screening of glycopeptide libraries
• Solid-phase carbohydrate synthesis

Covering state-of-the-art developments in the field, Solid Support Oligosaccharide Synthesis and Combinatorial Carbohydrate Libraries is a comprehensive resource for bioorganic and organic chemists, biochemists, and medicinal chemists.