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A greater knowledge of the basic molecular mechanisms which
regulate platelet function, coagulation, the fibrinolytic system
and their interaction with the vessel wall has allowed a better
understanding of the numerous aspects involved in the pathogenesis
of thrombosis and the regulation of hemostasis. Thrombosis
represents today one of the causes of death in the Western
hemisphere. Arterial thrombosis may lead to myocardial infarction,
cerebral and peripheral vascular diseases. Venous thrombosis, on
the other hand, is a complication of heart disease, surgery,
extensive trauma, several obstetric pathologies, and may, at times,
develop in apparently healthy subjects. These complex problems are
dealt with within the content of "Advances in Hemostasis and
Thrombosis." The present papers contain up-to-date information on
hemostasis, the role of prostaglandins, fibrinolytic coagulation,
rheology, and modern therapeutic approaches along with their
clinical application. This book, therefore, offers the reader the
opportunity to profit from a rare encounter, an interdisciplinary
cooperation, with scientific contributions from numerous countries.
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