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Reflecting current techniques and practical experience of continued
deterioration of reinforced concrete structures, this revised and
updated edition brings together the fundamental aspects of this
worldwide problem, and offers advice on how investigations,
diagnosis and consequent remedial work should be carried out. It
covers reinforced concrete buildings, water-retaining and
water-excluding structures, marine structures and bridges. The nine
chapters also cover deterioration and renovation of concrete
floors, repair and waterproofing of concrete roofs. The
deterioration of concrete liquid retaining structures, including
sewers, caused by chemical attack is also discussed and suggestions
made for remedial work. The author discusses the newer methods of
cathodic protection, realkalization and desalination to inhibit
corrosion of reinforcement in existing structures.
A wealth of recent research into the continued deterioration of
reinforced concrete structures has led to a review of methods of
investigation and repair techniques. This thoroughly revised and
updated new edition brings together the fundamental aspects of this
world wide problem and offers advice on how investigations,
diagnosis and consequent remedial work should be carried out.
Prior to 1974, the ~adrenergic receptors were known only in-
directly as entities that responded to drugs in a selective manner
to mediate a variety of physiologically important responses. During
the intervening years, our view of ~adrenergic receptors has
changed dramatically. The availability of high affinity
125I-labeled radioligands selective for these receptors presaged an
explosion of experimenta- tion utilizing direct binding assays to
establish the biochemical properties of the receptor protein. In
the opening chapter, Stadel and Lefkowitz describe this development
and its impact on our under- standing of the molecular basis of
~adrenergic receptor function. The availability of
well-characterized receptor ligands, coupled with the development
of efficient methods for detergent solubilization, formed the basis
of receptor purification using affinity chromatography. The related
technique of photoaffinity labeling provided a means to estimate
the molecular mass of these receptors. The availability of
substantial amounts of purified ~2-adrenergic receptor allowed
determination of segments of its amino acid se- quence. This
information led to the production of polynucleotide probes and
eventually to cloning of the receptor gene and determi- nation of
the complete primary sequence of the receptor protein. Caron and
Lefkowitz review the investigations leading to this major
development and discuss the methods involved. They analyze our
current perception of the relation of receptor function to its
structure and discuss the general features of the G
protein-interacting receptor family, of which the ~-adrenergic
receptors are prototypes.
Prior to 1974, the ~adrenergic receptors were known only in-
directly as entities that responded to drugs in a selective manner
to mediate a variety of physiologically important responses. During
the intervening years, our view of ~adrenergic receptors has
changed dramatically. The availability of high affinity
125I-labeled radioligands selective for these receptors presaged an
explosion of experimenta- tion utilizing direct binding assays to
establish the biochemical properties of the receptor protein. In
the opening chapter, Stadel and Lefkowitz describe this development
and its impact on our under- standing of the molecular basis of
~adrenergic receptor function. The availability of
well-characterized receptor ligands, coupled with the development
of efficient methods for detergent solubilization, formed the basis
of receptor purification using affinity chromatography. The related
technique of photoaffinity labeling provided a means to estimate
the molecular mass of these receptors. The availability of
substantial amounts of purified ~2-adrenergic receptor allowed
determination of segments of its amino acid se- quence. This
information led to the production of polynucleotide probes and
eventually to cloning of the receptor gene and determi- nation of
the complete primary sequence of the receptor protein. Caron and
Lefkowitz review the investigations leading to this major
development and discuss the methods involved. They analyze our
current perception of the relation of receptor function to its
structure and discuss the general features of the G
protein-interacting receptor family, of which the ~-adrenergic
receptors are prototypes.
"The Art and Science of Communication" shows you a new way to
understand and use communication in the workplace. Revealing the
seven types of communication we all use every day, the book shows
you how to increase your communication effectiveness in any setting
with practical techniques, analogies, and models that clearly
explain the formulas for successful communication. Combining the
science and art of communication into one effective formula, this
book offers a straightforward and easy to understand plan for a
more successful career.
So you think you want to start a business? Where do you begin? One
of your best initial investments is buying this book. The author
takes you through a step-by-step process to see just how ready you
are to become a business owner. No matter what business you are
planning, it's important to understand the commitment, training and
knowledge you will need to be a successful entrepreneur. If owning
your own business is a dream you have always had, then get started
today and find out what it takes to start your own
business...before you invest a dime Running a small business is
hard work. In a tough economy it can even be harder. You may have a
great team. A solid idea. Strong will to succeed. But if you don't
ask and then answer the right questions, your struggles may lead to
failure. This book is filled with real-world advice and practical
know-how, built on sound entrepreneurial principles, and is a must
read for anyone moving from being empolyed by someone else to being
self-empolyed. Each chapter contains a self-assessment tools that
is particularly helpful and packs a powerful punch of reality.
There is a place in the book to journal your progress from where
you are today to where you want to be tomorrow This book is more
than just a read - it is an interactive experience
A child abandoned. A life destroyed. Two hearts, unable to
forgive... After a drunk driver leaves young Cassie Belanger an
orphan, a cryptic letter sends her on a desperate journey to find
her father. Driven by anger, her bitterness and her desire to
confront the man who abandoned her, Cassie meets Jack, a crusty old
bachelor headed in the same direction. In his face Cassie begins to
see what can happen to a heart that refuses to forgive. Will she
find the power that lies in forgiveness and the miracle of God's
unwavering mercy? The answers lie... Just Past Oysterville.
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