This book highlights recent advances in variety of nanomaterials classes including metal chalcogenides, metal oxides/hydroxides, polymer, metal-organic frameworks, and hybrid nanostructures, with a focus on their properties, synthesis methods, and key applications. It also offers detailed coverage on the toxicity aspects with possible solution. Additionally, it provides complete and comprehensive information on surface modification strategies of nanoparticles to achieve desired outcomes. This book discusses potential applications and major challenges of using these nanomaterials in the fields of biomedical sciences, agricultural industry, bioenergy, biofuel production, and environmental remediation, etc. Overall, this book provides crucial background in nanobiotechnology that compliments the understanding of experimental design for the production of more customized nanomaterials to avail desirable benefits.

RNAi technology are used for large-scale screens that systematically shut down each gene in the cell, which can help identify the components necessary for a particular cellular process or an event such as cell division. Exploitation of the pathway is also a promising tool in biotechnology and medicine. This book reviews the selective and robust effect of RNAi on gene expression which makes it a valuable research tool, both in cell culture and in living organisms because synthetic dsRNA introduced into cells can induce suppression of specific genes of interest. This book will introduce new technology in the study of RNA interference in microorganisms, plants and animals.

Sarcoidosis is a complex multisystem disease. Shortness of breath (dyspnea) and a cough that won't go away can be among the first symptoms of sarcoidosis, but sarcoidosis can also show up suddenly with the appearance of skin rashes and other dermatoses.

An Atlas of Sarcoidosis: Pathogenesis, Diagnosis and Clinical Features combines illustrations and clinical images of the authors' extensive practices, so that readers have unparalleled access to a comprehensive collection of sarcoidosis images. The atlas is designed to complement and provide a visual supplement to already existing texts on sarcoidosis. Each organ involvement is dealt in a brief and easy to comprehend manner. Various radiographic and laboratory abnormalities are then linked to the clinical features in order to encourage a smooth and easy practical integration at the bedside and to help practising pulmonologists, dermatologists and other clinicians who require a comprehensive visual encyclopedia of sarcoidosis images.

RNAi technology are used for large-scale screens that systematically shut down each gene in the cell, which can help identify the components necessary for a particular cellular process or an event such as cell division. Exploitation of the pathway is also a promising tool in biotechnology and medicine. This book reviews the selective and robust effect of RNAi on gene expression which makes it a valuable research tool, both in cell culture and in living organisms because synthetic dsRNA introduced into cells can induce suppression of specific genes of interest. This book will introduce new technology in the study of RNA interference in microorganisms, plants and animals.

Stem Cells and COVID-19 presents up-to-date knowledge on the effect of hematopoietic and mesenchymal stem cells to combat SARS-CoV-2 infection in its diagnosis, treatment and prevention. In addition, the book critically discusses challenges, highlighting outstanding questions and future perspectives. Written by global experts in the field for both pre-clinical and clinical practitioners, this comprehensive book delves into how stem cells have a strong potential in developing better diagnostic, treatment and preventive strategies in SARS-CoV-2 infection. Both hematopoietic and mesenchymal stem cells are critical to better understand the response of immune system to coronavirus infection in both healthy and co-morbid conditions in the development of effective vaccines and immunotherapies.

Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue. Biointegration of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering. With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector.

Biointegration of Medical Implant Materials, Second Edition, provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. New sections discuss soft tissue integration, with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering, and vascular grafts. Other sections review tissue regeneration, inorganic nanoparticles for targeted drug delivery, alginate based drug delivery devices, and design considerations, with coverage of the biocompatibility of materials and their relevance to drug delivery and tissue engineering. With its distinguished editor and team of international contributors, this book is ideal for medical materials scientists and engineers in industry and academia.