This two-volume book provides the first comprehensive survey of opioid research, a field which has accumulated a tremendous amount of literature since the identification of opioid receptors and their endogenous ligands. In more than 60 chapters experts present state-of-the-art reviews of this fascinating field, the topics ranging from molecular biology to clinical applications. Part I covers the multiplicity of opioid receptors, the chemistry of opiates and opioid peptides as well as the neurophysiology of opioids. Part II reviews a broad spectrum of physiological and behavioral functions and pharmacological actions of opioids, together with their neuroendocrinology, opioid tolerance and dependence, concluding with pathophysiological aspects and clinical use.

Anesthesiology and the Cardiovascular Patient contains the edited presentations of the 41st Annual Postgraduate Course in Anesthesiology, February 1996. The chapters reflect new data and concepts within the general framework of the pathophysiology and management of surgical candidates with cardiovascular disease. The textbook will serve as a vehicle to bring many of the latest concepts in anesthesiology to those who did not attend the conference. Each chapter is a brief but sharply focused glimpse of the current interest in anesthesia. This volume, as well as past and future volumes, reflects the rapid and continuing evolution of anesthesiology in the late twentieth century.

Anesthesiology and the Cardiovascular Patient contains the edited presentations of the 41st Annual Postgraduate Course in Anesthesiology, February 1996. The chapters reflect new data and concepts within the general framework of the pathophysiology and management of surgical candidates with cardiovascular disease. The textbook will serve as a vehicle to bring many of the latest concepts in anesthesiology to those who did not attend the conference. Each chapter is a brief but sharply focused glimpse of the current interest in anesthesia. This volume, as well as past and future volumes, reflects the rapid and continuing evolution of anesthesiology in the late twentieth century.