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Bioorganic and bioinorganic chemistry and two leading disciplines at the interface of chemistry and biology. Now there is an increasing number of both chemists and biochemists who are studying simple synthetic molecules as models of enzymes. Molecular recognition is an important concept on which these research efforts are based. Supramolecular chemistry based on noncovalent intermolecular forces has provided the most important innovations in organic, inorganic and biochemistry in the recent past. The award of the Nobel prize in chemistry for 1987 to D J Cram, J M Lehn and C J Pedersen reflects the importance of the topics mentioned above. This book is written to serve as a textbook which is a blend of the most important concepts of bioorganic, bioinorganic and supramolecular chemistry.
The text is ideal for under and postgraduate students of biophysical chemistry and as a handy guide for researchers in industry and biotechnology. This text covers: The study of biological cell and its organisation Bioenergetics Statistical Mechanics in biopolymers Forces involved in biopolymer interactions Cell membrane and solute transport Biopolymers and their molecular weights Thermodynamics of biopolymer solutions Diffraction methods and study of macromolecules
The book is designed to provide a comprehensive coverage in the area of organic reaction mechanism for a chemistry major/graduate student. The practice of medicine now increasingly demands a knowledge of the behaviour of molecules. Therefore, the biologist of tomorrow will have to be more of an organic chemist, among other things. The books is thus aimed at Pharmacologists, Medical chemists and Biochemists also.
PHARMACEUTICAL, MEDICINAL AND NATURAL PRODUCT CHEMISTRY provides an overview of structural features and functional groups of different classes of pharmacologically active natural products, synthetic drugs and drugs from microorganisms, animals and plants and their biological activities. The text presents the concepts which are central to the study of drug action of the natural materials themselves and as lead compounds and drug production (DNA Recombinant Technology) supported by logical chemical, biochemical and mechanistic principles. The material presented guides the reader through biosynthetic and metabolic pathways, which demonstrates their unique integration. The book also contains material on the synthesis of some drugs structure, synthesis, biosynthesis and conformational analysis of some of the more important members of terpenoids, steroids, carotenoid alkaloids, flavanoids, purine and pyrimidines along with their medicinal significance. Students of organic chemistry, pharmacy and medicinal chemistry will find this book an invaluable source.
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