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Antiplatelet therapy is the cornerstone of treatment of ischemic
cardiovascular disease and over the last few years spectacular
advancements in this field have been recorded. This is the first
comprehensive handbook entirely dedicated to all the aspects of
antiplatelet therapy. The book is divided into three main sections,
pathophysiology, pharmacology and therapy, for a total of 23
chapters. A large group of leading experts from different European
countries and from the USA, both from academia and industry, have
contributed to the book. Besides a detailed overview on the
pharmacology and clinical applications of all the currently used or
of the novel antiplatelet agents, innovative approaches (e.g.
intracellular signalling as an antiplatelet target, small RNAs as
platelet therapeutics, etc.) or unconventional aspects (e.g.
pharmacologic modulation of the inflammatory action of platelets
are also treated. The book is oriented to both basic investigators
and to clinicians involved with research on platelet inhibition or
with the clinical use of antiplatelet therapies.
Antiplatelet therapy is the cornerstone of treatment of ischemic
cardiovascular disease and over the last few years spectacular
advancements in this field have been recorded. This is the first
comprehensive handbook entirely dedicated to all the aspects of
antiplatelet therapy. The book is divided into three main sections,
pathophysiology, pharmacology and therapy, for a total of 23
chapters. A large group of leading experts from different European
countries and from the USA, both from academia and industry, have
contributed to the book. Besides a detailed overview on the
pharmacology and clinical applications of all the currently used or
of the novel antiplatelet agents, innovative approaches (e.g.
intracellular signalling as an antiplatelet target, small RNAs as
platelet therapeutics, etc.) or unconventional aspects (e.g.
pharmacologic modulation of the inflammatory action of platelets
are also treated. The book is oriented to both basic investigators
and to clinicians involved with research on platelet inhibition or
with the clinical use of antiplatelet therapies.
This book reviews current science and applications in fields
including thrombosis and hemostasis, signal transduction, and
non-thrombotic conditions such as inflammation, allergy and tumor
metastasis. It is a detailed, up-to-date, highly referenced text
for clinical scientists and physicians, including recent
developments in this rapidly expanding field. More than a
scientific resource, this is also an authoritative reference and
guide to the diagnosis.
A rapid increase in our understanding of the biology of platelets
and their role in disease in recent years has been paralleled by
increasing successes with established platelet-modifying therapies
in many clinical conditions. This text focuses on the clinical role
of platelets in a wide variety of haematologic, cardiovascular and
other disorders, providing a practical, clinically relevant
handbook for all clinicians and researchers interested in platelets
and their role in disease. Covering platelet physiology, bleeding
disorders, thrombotic disorders and antithrombotic therapy.
Chapters cover all the conventional and less conventional aspects
of platelet involvement in disease, with an emphasis on recent
clinical developments. Clear take home messages have been included
in each chapter to aid clinical practice. With contributions from
leading experts across three continents, Platelets in Hematologic
and Cardiovascular Disorders is an up-to-date, well illustrated,
practical resource for everyone involved in clinical practice with
platelet disorders.
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