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This first edited Volume on IgY-Technology, addresses the
historical and dynamic development of IgY-applications. The authors
cover the biological basis and theoretical context, methodological
guidance, and applications of IgY-Technology. A focus is laid on
the use of IgY-antibodies for prophylactic/therapeutic purposes in
human and veterinary medicine. Aside from applications, the
chapters also offer an evolutionary understanding of the IgY
molecule, IgY receptors and practical prerequisites to produce
IgY-antibodies. Guidance is given for every step of the process.
Starting with an introduction to hens as a model species and
including hen husbandry, hen egg-laying capacity and total IgY
outcomes. Readers will also learn about immunization techniques,
the advantages and limitations of different IgY extraction methods,
as well as storage stability of the final product. The last part of
the volume highlights hands-on aspects of applications, such as IgY
delivery strategies, new methods to produce monoclonal
IgY-antibodies or production of functional IgY fragments by
phage-display as well as commercial exploitation of the technology.
Thus, this book is a valuable resource and guide for Scientists,
Clinicians and Health Product Developers in both human and
veterinary medicine.
In a new study, Patricia Morgan shows how tax and benefits policy
has undermined family life in Britain and encouraged fraud and
dishonesty. The study shows how the tax and benefits systems are
particularly harsh on single-earner couples who have to earn over
GBP50,000 before there is no loss from declaring their relationship
to the authorities. This situation encourages couples not to marry
and, if they are living together, to lie to the authorities about
their family situation. In 2004/05, the government paid credits and
benefits to 200,000 more lone parents than actually live in the UK
-- fraud is widespread. The tax and benefits system encourages such
fraud. In the most extreme case, a couple can gain nearly GBP10,000
a year by not declaring their relationship. Family life has been
discouraged over 25 years by both Conservative and Labour
governments. In the Thatcher years, the Conservative government
gave lone parents special financial benefits and priority
entitlement to council housing. In the Labour years, the state
increasingly became the child-care provider. As Patricia Morgan
comments, "Under Thatcher, the state became the bread-winner for
lone parents; under Brown the state became the child carer. The
consequences are obvious -- couples are strongly encouraged not to
commit to each other because, by doing so, they will lose out
financially. Both Conservative and Labour governments also removed
any offsetting compensation in the tax system that had previously
helped two-parent families." Government policy penalising
two-parent families has had a disastrous economic and social
effect. Couples who describe themselves as "closely involved" are
twelve times more likely than married couples to split up in the
first three years of a childs life. There are also higher levels of
worklessness and benefit dependency -- lone parent families
receiving an average of 66% of their income in benefits and tax
credits. Morgan shows how it is clear from international evidence,
examining trends over time and by looking at the behaviour of
individuals on different levels of income, that the tax and
benefits system has caused the increase in lone parent families.
Where there are no incentives for lone parenthood, couples tend to
stay together, marry and ensure that they can support their
children independently of the state. Individuals and couples
respond rationally to the incentives they face -- currently the
government is giving families perverse incentives, encouraging them
not to form stable family units. Major changes in the tax and
benefit system are necessary. Benefits to lone parents could be
reduced. Also, the perverse incentives in the benefits system that
discourage couples from committing together should be offset by a
tax system that recognises families. In particular, families should
be allowed to allocate the income of the main earner to non-earners
in the family for tax purposes. Reforms to the tax and benefits
system should be bolstered by reforms to the "no fault" divorce
laws that currently allow a guilty party to walk away from their
marriage contract whilst imposing financial penalties on the
injured party.
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