Clinical Neurophysiology: Basis and Technical Aspects, the latest release in the Handbook of Clinical Neurology series, is organized into sections on basic physiological concepts, on the function and limitations of modern instrumentation, and on other fundamental or methodologic aspects related to the recording of various bioelectric signals from the nervous system for clinical or investigative purposes. There is discussion of the EEG, nerve conduction studies, needle electromyography, intra-operative clinical neurophysiology, sleep physiology and studies, the autonomic nervous system, various sensory evoked potentials, and cognitive neurophysiology.

Gain confidence and expertise with stereoelectroencephalography (SEEG) as a presurgical method for epilepsy with this helpful resource. Edited and written by leading experts in the field, Stereoelectroencephalography teaches the scientific and medical bases of SEEG through its essential disciplines (anatomy, biophysics, electrophysiology, and cognitive and behavioral neuroscience) and their interrelations. It fully covers the basic and clinical aspects of the pharmaco-resistant epilepsies investigated with SEEG and their surgical indications. Describes the evolution in time of the presurgical methods leading to the current practice of SEEG. Explains how to determine the anatomical basis of electrode implantation, its referential system, and how it prepares rational planning to tailored resection or ablation. Examines the nature of the SEEG signal, how the depth electrodes capture it, and how the dynamics of multiple cortical sites recording can be understood. Contains chapters on key topics such as the optimal SEEG electrode, intracerebral electrodes implantation technique, seizure onset: interictal, preictal/ictal patterns and the epileptogenic zone, how to define the extent of the EZ by applying signal processing methods, the role of SEEG in exploring lesional epilepsy cases, and much more. Presents the logical chain linking SEEG to anatomically pre-planned surgery. Includes discussions of in-depth illustrative cases. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. N/A

Clinical case studies have long been recognized as a useful adjunct to problem-based learning and continuing professional development. They emphasize the need for clinical reasoning, integrative thinking, problem-solving, communication, teamwork and self-directed learning - all desirable generic skills for health care professionals. Epilepsy is amongst the most frequently encountered of neurological disorders. There are important emerging clinical management issues (e.g., first seizure, therapy-resistant seizures, ICU, pregnancy) but also differential diagnosis of non-epileptic seizures (syncopy, pseudo-seizure, paroxysmal dystonic syndromes, sleep disorders, psychosis, inborn errors of metabolism, etc.). This selection of epilepsy case studies will inform and challenge clinicians at all stages in their careers. Including both common and uncommon cases, Case Studies in Epilepsy reinforces the diagnostic skills and treatment decision-making processes necessary to treat epilepsy and other seizures confidently. Written by leading experts, the cases and discussions work through differential diagnoses, treatments and social consequences in pediatric and adult patients.

A 'generalised seizure' corresponds to an ictal manifestation whose initial semeiology indicates or is consistent with more than minimal involvement of both cerebral hemispheres. A 'network' is a functionally and automatically connected set of cortical and subcortical brain regions in which activity in any one part affects activity in all others. A 'system' is a group of independent but interrelated elements (networks) comprising a unified whole. A considerable amount of evidence supports the existence of cortical and subcortical networks in the genesis, expression and control of generalised seizures. Animal and human data suggested that the so-called generalised seizures involve selective networks while sparing others. A greater understanding of those systems and networks is thoroughly debated in this book.