This book constitutes the refereed proceedings of the 10th International Conference on Evolutionary Multi-Criterion Optimization, EMO 2019 held in East Lansing, MI, USA, in March 2019. The 59 revised full papers were carefully reviewed and selected from 76 submissions. The papers are divided into 8 categories, each representing a key area of current interest in the EMO field today. They include theoretical developments, algorithmic developments, issues in many-objective optimization, performance metrics, knowledge extraction and surrogate-based EMO, multi-objective combinatorial problem solving, MCDM and interactive EMO methods, and applications.