This book covers biotechnology and applications of diatoms including various applications like the use of diatom biogenic silica in drug delivery and their cultivation for wastewater remediation. It contains case studies in diatom biorefinery and provides information about the bioactive compounds, antioxidants, and lipids from diatoms. It also discusses the latest innovations in the genetic engineering of diatoms. Key Features - Discusses the applications of diatoms in drug delivery Covers the application and cultivation of diatoms for wastewater bioremediation Describes the innovations and gaps in genetic engineering of diatoms Throws light on the lipid content, antioxidant content, and various bioactives compounds present in diatoms Includes extraction technologies in diatoms The book is meant for academicians and microbiologists, biotechnologists, and marine biologists.

This reference book covers the ecological impact and biotechnological applications of diatoms. Diatoms contribute to forty percent of primary productivity in aquatic ecosystems. They have a unique biomonitoring ability and sensitivity towards different pollutants in wastewater, thereby a tool for ecotoxicological monitoring. The book discusses the need for newer diatoms-based indices for wastewater quality analysis. It describes the nutraceutical value of the myriad compounds like omega 3 fatty acids-DHA, polysaccharides, phenols in diatoms. It also elaborates on the challenges in sustainable diatom biorefinery. This book is meant for microbiologists, biotechnologists, and marine biologists.

This is the first book to present the idea of Industry 5.0 in biomanufacturing and bioprocess engineering, both upstream and downstream. The Prospect of Industry 5.0 in Biomanufacturing details the latest technologies and how they can be used efficiently and explains process analysis from an engineering point of view. In addition, it covers applications and challenges. FEATURES Describes the previous Industrial Revolution, current Industry 4.0, and how new technologies will transition toward Industry 5.0 Explains how Industry 5.0 can be applied in biomanufacturing Demonstrates new technologies catered to Industry 5.0 Uses worked examples related to biological systems This book enables readers in industry and academia working in the biomanufacturing engineering sector to understand current trends and future directions in this field.

This is the first book to present the idea of using Industry 4.0 and smart manufacturing in the microalgae industry for environmental biotechnology. It provides the latest developments on microalgae for use in environmental biotechnology, explains process analysis from an engineering point of view, and discusses the transition to smart manufacturing and how state of the art technologies can be incorporated. It covers applications, technologies, challenges, and future perspectives. * Showcases how Industry 4.0 can be applied in algae industry * Covers new ideas generated from Industry 4.0 for Industrial Internet of Things (IIoT) * Demonstrates new technologies invented to cater to Industry 4.0 in microalgae * Features worked examples related to biological systems Aimed at chemical engineers, bioengineers, and environmental engineers, this is an essential resource for researchers, academics, and industry professionals in the microalgae biotechnology field.

Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students.

Bioprocess Engineering: Downstream Processing is the first book to present the principles of bioprocess engineering, focusing on downstream bioprocessing. It aims to provide the latest bioprocess technology and explain process analysis from an engineering point of view, using worked examples related to biological systems. This book introduces the commonly used technologies for downstream processing of biobased products. The covered topics include centrifugation, filtration, membrane separation, reverse osmosis, chromatography, biosorption, liquid-liquid separation, and drying. The basic principles and mechanism of separation are covered in each of the topics, wherein the engineering concept and design are emphasized. This book is aimed at bioprocess engineers and professionals who wish to perform downstream processing for their feedstock, as well as students.

Principles of Multiple-Liquid Separation Systems: Interaction, Application and Advancement describes the basic principles and advancements of multiple-liquid separation systems in downstream processing. Several important elements are included, such as the fundamental process and mechanisms of the multiple-liquid separation system, key principles of the interaction between different solvents and phase components, applications, and green solvents for the separation system. Furthermore, the book gives insights in commercializing this separation technique to industrial scale and making the process environmentally and economically sustainable. The book also presents constructive critics of this separation technique for both past and the latest findings.

This book elucidates the sustainable production of commercially important biomolecules in medicines, food, and beverage processing, through biological systems, including microorganisms, animal cells, plant cells, tissues, enzymes, and in vitro. It discusses promising technologies for the manipulation of cells including, genetic engineering, synthetic biology, genome editing, and metabolic engineering. The initial chapters of the book introduce topics on biomanufacturing, circular economy, strain design and improvement, upstream and downstream processing. The subsequent chapters cover artificial intelligence-assisted production, designer cell factories, biosensors for monitoring biomolecules, different cells factories, biosynthetic pathways, and genome editing approaches for scale-up biomanufacturing. Lastly, the book discusses the opportunities and challenges of implementing biological systems for the production of biomolecules. This book is a valuable source for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand biomanufacturing for the sustainable production of biomolecules.

Downstream bioprocesses have a significant role to play in the creation of a sustainable bio-based economy, enabling the creation of new products and systems from the more sustainable bioprocessing of natural products. Liquid Biphasic System: Fundamentals, Methods, and Applications in Bioseparation Technology explores in detail the fundamental processes and applications of this new separation system, aiding understanding of the basic principles of the technique and offering constructive criticisms on the latest findings. Including coverage of the background, principles, mechanisms, and applications, Liquid Biphasic System addresses how to adapt the technology for the purification of useful compounds with greater cost efficiency and greener processing. It is essential reading for bioprocess engineers, biochemical engineers, biosystem engineers, chemists and microbiologists working in the fields of bioprocessing. Researchers, scientists, and engineers concerned with the selection and evaluation of alternative bioseparation processes will find the book particularly useful.