The vaccines most urgently needed are those againstpoverty-related diseases such as tuberculosis, malaria and HIV.However, there is a considerable gap between the development of avaccine and the implementation as a useful measure for diseasecontrol. Major obstacles need to be overcome even after successfulcompletion of the preclinical stage.

This book provides an important link between vaccine developmentand application under the particular conditions in developingcountries.
The editors, S.H.E. Kaufmann and P.H. Lambert - one from the fieldof basic research and the other an expert on the side of appliedvaccinology - have gathered contributions from specialists of bothfields in an attempt to create a source of information that hasthus far not been available.

The Vaccine Book, Second Edition provides comprehensive information on the current and future state of vaccines. It reveals the scientific opportunities and potential impact of vaccines, including economic and ethical challenges, problems encountered when producing vaccines, how clinical vaccine trials are designed, and how to introduce vaccines into widespread use. Although vaccines are now available for many diseases, there are still challenges ahead for major diseases, such as AIDS, tuberculosis, and malaria. This book is designed for students, researchers, public health officials, and all others interested in increasing their understanding of vaccines. It answers common questions regarding the use of vaccines in the context of a rapidly expanding anti-vaccine environment. This new edition is completely updated and revised with new and unique topics, including new vaccines, problems of declining immunization rates, trust in vaccines, the vaccine hesitancy, and the social value of vaccines for the community vs. the individual child's risk.