This innovative monograph introduces a measurement-based framework for effective treatment of patients with mood disorders, personality disorders, and schizophrenia. Rooted firmly in principles of pharmacotherapy and clinical psychometrics, the book's signature diagram balances rating scale results and patient self-reported progress along three angles: therapeutic effects, adverse effects, and quality of life. The author's choices of measures are brief, valid, widely used, and easy for clinicians to administer and patients to understand. But rather than being a mechanistic or an impersonal formula, this system is shown as a science-based means of fostering constructive collaboration between patient and therapist, leading to greater patient well-being. Included in the coverage: * Negative mental health: the ordinary symptom-orientated mental disorders. * The basic diagram of personality dimensions. * Self-reported symptom scales within the basic diagram. * Clinician-administered symptom scales within the basic diagram. * The pharmacopsychometric triangle in measurement-based care. * Diagnostic rating scales. * A practical outcome evaluation plan. Offering a medical level of precision to mental health, Measurement-Based Care in Mental Disorders should interest health care providers at all levels, particularly physicians and staff in primary care settings, and in psychiatric in- and outpatient clinics, including psychiatrists, psychologists, nurses, and social workers.

The European College of Neuropsychopharmacology (ECNP) is a scientific and educational association which represents a variety of disciplines. The first ECNP congress took place in Copenhagen, May 1985, where a working group of European scientists within the field of psychopharmacology was elected to prepare a constituent ECNP congress in Brussels, 1987. Among the most active members of this group was Max Hamilton. At the second ECNP congress in Brussels Max Hamilton was elected as the first honorary member of the ECNP. When we received the message of his death we decided at once to arrange a Max Hamilton memorial symposium at the third ECNP congress, May 1989, in Gothenburg, Sweden. This monograph contains the proceedings of the Max Hamilton symposium which was chaired by the editors. The opening lecture of the third ECNP congress was a Max Hamilton lecture: "A life devoted to science in psychiatry" which was presented by Sir Martin Roth. It seemed obvious to include Sir Martin's lecture as the opening article of this monograph. Although G .E. Berrios was unable to participate in the ECNP congress we have found it logical to include his manuscript on "The Hamilton Depression Scale and the Numerical Description of the Symptoms of Depression" as another personal contribution to Max Hamilton and his rating scales.

In its second edition this volume covers the most frequently used mood rating scales such as the Hamilton Depression Scale (HAM-D) and the Zung Scale. The Major Depression Rating Scale has been revised to correspond more strictly to ICD-10. A new appendix combines didactically the WHO (Ten) Well-Being Questionnaire, the WHO (ICD-10) criteria for depression, and the Major Depression Rating Scale. Furthermore, the Calgary Depression Scale for Schizophrenia has been included. The scoring sheets and the corresponding manuals of the scales are presented along with documentation of both internal (coherence) and external (discriminating and predictive) validity.

This book has grown out of a previous publication, the Mini-compendium (Bech et al. 1986), which was developed as a guide both for clinical research and for the documentation of routine activities in assessing psychiatric disability, whether in a general hospital, by a district psychiatrist or a nurse, by a liaison-consultant psy- chiatrist, by a clinical psychologist, by a health worker, or in general practice. One of its outstanding merits was that its scales were authoritative: During its prepara- tion Max Hamilton corrected and finally accepted the English versions of his scales and Ole Rafaelsen corrected the English versions of the remaining scales. While preparing this publication we were constantly reminded of how difficult it is to accept that Max and Ole are no longer with us. _ One indication of the success of the Mini-compendium is the fact that it was ttanslated into a number of languages, including Spanish (Ballus and Tressera, 1988), Italian (Fava and Grandi, 1988), French (pichot et al. 1989), Dutch (D'haenen and Verhoeven, 1989), and German (Maier et al. 1991). Another indi- cation was its correspondence to the DSM-III (APA, 1980) criteria for anxiety, depression, mania and schizophrenia. This volume refers to DSM-III-R (APA, 1987) and ICD-IO (WHO, 1992).

Dieses Buch versucht, mit Hilfe internationaler anerkannter Ratinskalen und standardisierten Beurteilungsverfahren deut- lich operationelle Definitionenf}r die vier klassischen Konzepte in der nichtorganischen oder funktionellenPsycha- trie (Angst, Depression, Manie und Schizophrenie) anzubie- ten.