|
Showing 1 - 6 of
6 matches in All Departments
Nanoparticles have a physical dimension comparable to the size of
molecular structures on the cell surface. Therefore, nanoparticles,
compared to larger (e.g., micrometer) particles, are considered to
behave differently when they interact with cells. Nanoparticles in
the Lung: Environmental Exposure and Drug Delivery provides a
better understanding of how inhaled nanoparticles behave in the
human lungs and body. Featuring contributions from renowned
subject-matter experts, this authoritative text describes the
sequence of events that nanoparticles encounter in the lungs when
moving from the air into the bloodstream. This includes deposition,
interactions with the alveolar surface and epithelium,
translocation across the air-blood tissue barrier, and accumulation
in the body. In addition, the book addresses practical
considerations for drug delivery to the respiratory tract, drug and
gene delivery in the lungs, and bio-nanocapsules. It considers the
physicochemical, colloidal, and transport properties of
nanoparticles, and presents cutting-edge research on special issues
such as dosimetry for in vitro nanotoxicology, nanoparticle
deposition in the developing lungs, and the potential for
nose-to-brain delivery of drugs. Nanoparticles in the Lung:
Environmental Exposure and Drug Delivery offers the most updated
and comprehensive knowledge of the risks and benefits associated
with nanoparticle inhalation-to protect humans from any harmful
effects and to explore the utility of nanoparticles as drug
delivery carriers.
Why the "Second Edition" is the must-have guide for all
pulmonologists and particle research scientists:
STAY INFORMED - nine brand new chapters cover recent developments
and research, with several chapters focusing solely on the
fast-developing area of man-made and naturally occurring nano-sized
particles
GAIN FULL UNDERSTANDING OF ALL ASSOCIATED DISCIPLINES - including
topics and concerns in pulmonology and respiratory medicine,
toxicology, and environmental research
KNOW WHAT TO EXPECT as a disease progresses, from a distinguished
team of over 40 experts who detail all stages of particle-lung
interactions, from inhalation of particles to clearance from the
organism
LEARN MORE ABOUT FREQUENTLY NEGLECTED TOPICS - such as the
beneficial developments and uses of inhaled man-made particles and
reduced side-effects of alternate therapies
Nanoparticles have a physical dimension comparable to the size of
molecular structures on the cell surface. Therefore, nanoparticles,
compared to larger (e.g., micrometer) particles, are considered to
behave differently when they interact with cells. Nanoparticles in
the Lung: Environmental Exposure and Drug Delivery provides a
better understanding of how inhaled nanoparticles behave in the
human lungs and body. Featuring contributions from renowned
subject-matter experts, this authoritative text describes the
sequence of events that nanoparticles encounter in the lungs when
moving from the air into the bloodstream. This includes deposition,
interactions with the alveolar surface and epithelium,
translocation across the air-blood tissue barrier, and accumulation
in the body. In addition, the book addresses practical
considerations for drug delivery to the respiratory tract, drug and
gene delivery in the lungs, and bio-nanocapsules. It considers the
physicochemical, colloidal, and transport properties of
nanoparticles, and presents cutting-edge research on special issues
such as dosimetry for in vitro nanotoxicology, nanoparticle
deposition in the developing lungs, and the potential for
nose-to-brain delivery of drugs. Nanoparticles in the Lung:
Environmental Exposure and Drug Delivery offers the most updated
and comprehensive knowledge of the risks and benefits associated
with nanoparticle inhalation-to protect humans from any harmful
effects and to explore the utility of nanoparticles as drug
delivery carriers.
In this book the recent progress accumulated in studies of the
interaction of engineered nanoparticles with cells and cellular
constituents is presented. The focus is on manufacturing and
characterization of nanosized materials, their interactions with
biological molecules such as proteins, the mechanisms of transport
across biological membranes as well as their effects on biological
functions. Fundamental molecular and cellular aspects are in the
foreground of the book. A further particularity is the
interdisciplinary approach, including fields such as preparatory
and analytical chemistry, biophysics and the physics of colloids,
advanced microscopy and spectroscopy for in-situ detection of
nanoparticles, cellular toxicology and nanomedicine. Nanoscale
particles are known to exhibit novel and unprecedented properties
that make them different from their corresponding bulk materials.
As our ability to control these properties is further advanced, a
huge potential to create materials with novel properties and
applications emerges. Although the technological and economic
benefits of nanomaterials are indisputable, concerns have also been
raised that nanoscale structuring of materials might also induce
negative health effects. Unfortunately, such negative health
effects cannot be deduced from the known toxicity of the
corresponding macroscopic material. As a result, there is a major
gap in the knowledge necessary for assessing their risk to human
health.
In this book the recent progress accumulated in studies of the
interaction of engineered nanoparticles with cells and cellular
constituents is presented. The focus is on manufacturing and
characterization of nanosized materials, their interactions with
biological molecules such as proteins, the mechanisms of transport
across biological membranes as well as their effects on biological
functions. Fundamental molecular and cellular aspects are in the
foreground of the book. A further particularity is the
interdisciplinary approach, including fields such as preparatory
and analytical chemistry, biophysics and the physics of colloids,
advanced microscopy and spectroscopy for in-situ detection of
nanoparticles, cellular toxicology and nanomedicine. Nanoscale
particles are known to exhibit novel and unprecedented properties
that make them different from their corresponding bulk materials.
As our ability to control these properties is further advanced, a
huge potential to create materials with novel properties and
applications emerges. Although the technological and economic
benefits of nanomaterials are indisputable, concerns have also been
raised that nanoscale structuring of materials might also induce
negative health effects. Unfortunately, such negative health
effects cannot be deduced from the known toxicity of the
corresponding macroscopic material. As a result, there is a major
gap in the knowledge necessary for assessing their risk to human
health.
Ein simples chemisches MolekA1/4l - CO2 - hat sich zu einer
Verbindung von hAchster politischer und wirtschaftlicher Brisanz
entwickelt. Die UniversitAt Bern fA1/4hrte im April 1995 in
Interlaken ein internationales interdisziplinAres Symposium A1/4ber
die CO2-Problematik, ihre mAglichen Auswirkungen auf das Klima, die
Vegetation und die Gesellschaft durch. FA1/4hrende PersAnlichkeiten
aus Wissenschaft, Politik, Wirtschaft und Affentlicher Verwaltung
diskutieren A1/4ber globale ZusammenhAnge des Kohlenstoffkreislaufs
zwischen Ozean und AtmosphAre, mAgliche Reaktionen der BiosphAre,
Beeinflussung von Temperatur und Niederschlag, biologische und
technische MAglichkeiten zur Gegensteuerung, sowie A1/4ber den
Einsatz marktwirtschaftlicher Instrumente zur Reduktion des
Treibhauseffektes.
|
You may like...
Loot
Nadine Gordimer
Paperback
(2)
R398
R330
Discovery Miles 3 300
Loot
Nadine Gordimer
Paperback
(2)
R398
R330
Discovery Miles 3 300
|