For decades, science and technology (sci-tech) have influenced world trade, world economy, and international finance. However, their specific impacts are seldom known and related empirical studies are rare. Thus, we must quantify and empirically explore how sci-tech influences such areas as mentioned above. The purpose of this book is to explore how sci-tech influences world trade, foreign exchange, and currency internationalization in various ways through quantifying science & technology first. This book empirically explores how major world currencies might change their relative international positions with continuous innovation and diffusion of sci-tech.Currency internationalization is measured by the percentage share of the average daily turnover of a particular currency in the global foreign exchange market over the corresponding overall daily turnover of the global foreign exchange market. Sci-tech as a commodity is borderless, yet its inventors and related businesses are bound by the intellectual property laws of their own countries. Patents, especially international patents, are useful representations of science & technology. They cannot be compared directly because of different criteria of patent regulators worldwide, and thus the quality of patents varies across patent regulators. Based on patent data from annual IP 5 Statistics Reports and charges for the use of IP of major currency issuers released by WTO, this book defines and quantifies sci-tech originality capability using data of charges for the use of IP of each economy and sci-tech internationalization using weighted patent families first, and proceeds to study how sci-tech internationalization affects currency internationalization.