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Many extrapyramidal motor diseases result from underlying
neurodegenerative processes, which however are very advanced at the
time the clinical diagnosis is made. From animal experiments it
seems likely that we may soon have several substances that provide
neuroprotective effects, but that their therapeutic use must be as
early as possible. This fact was the starting point for the
meeting, held at Chiemsee, that formed the basis of this book. The
idea was to develop in strumental methods that, first, permit an
earlier diagnosis by drawing on the experience of experts and,
second, provide a better resolution of successful therapy than the
currently used methods. As early as 1886, Charcot tried to
differentiate the tremor of polysclerosis and Parkinson patients by
using a drum developed by Marey, a physiologist. Subse quently,
many apparatuses were developed to better identify movement
disorders, initially for diagnostic purposes. Most of these methods
proved to be inferior to the skill of experienced observers. In the
last two decades, however, both the technical advances made in
measuring methods and the improvements achieved in methods of
evaluation have led to marked advances in the quantification of
motor dis turbances. An objective of the symposium held at Chiemsee
and of this book is to provide an overview of the procedures that
are currently commonly used for extrapyramidal movement disorders,
and to identify their potential and limitations."
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