Biological chemistry has changed since the completion of the human genome project. There is a renewed interest and market for individuals trained in biophysical chemistry and molecular biophysics. The Physical Basis of Biochemistry, Second Edition, emphasizes the interdisciplinary nature of biophysical chemistry by incorporating the quantitative perspective of the physical sciences without sacrificing the complexity and diversity of the biological systems, applies physical and chemical principles to the understanding of the biology of cells and explores the explosive developments in the area of genomics, and in turn, proteomics, bioinformatics, and computational and visualization technologies that have occurred in the past seven years. The book features problem sets and examples, clear illustrations, and extensive appendixes that provide additional information on related topics in mathematics, physics and chemistry.

Biophysical Chemistry: Molecules to Membranes is a one-semester textbook for graduate and senior undergraduate students. Developed over several years of teaching, the approach differs from that of other texts by emphasizing thermodynamics of aqueous solutions, by rigorously treating electrostatics and irreversible phenomena, and by applying these principles to topics of biochemistry and biophysics. The main sections are: (1) Basic principles of equilibrium thermodynamics. (2) Structure and behavior of solutions of ions and molecules. The discussions range from properties of bulk water to the solvent structure of solutions of small molecules and macromolecules. (3) Physical principles are extended for the non-homogenous and non-equilibrium nature of biological processes. Areas included are lipid/water systems, transport phenomena, membranes, and bio-electrochemistry. This new textbook will provide an essential foundation for research in cellular physiology, biochemistry, membrane biology, as well as the derived areas bioengineering, pharmacology, nephrology, and many others.

advanced undergraduate/beginning graduate level students and would be applied to courses focusing on three different areas:

Foundations of molecular biophysics
Macromolecular structure and assembly
Methods in physical biochemistry

Biological chemistry has changed since the completion of the human genome project. There is a renewed interest and market for individuals trained in biophysical chemistry and molecular biophysics. The Physical Basis of Biochemistry, Second Edition, emphasizes the interdisciplinary nature of biophysical chemistry by incorporating the quantitative perspective of the physical sciences without sacrificing the complexity and diversity of the biological systems, applies physical and chemical principles to the understanding of the biology of cells and explores the explosive developments in the area of genomics, and in turn, proteomics, bioinformatics, and computational and visualization technologies that have occurred in the past seven years. The book features problem sets and examples, clear illustrations, and extensive appendixes that provide additional information on related topics in mathematics, physics and chemistry.

Tools for Modeling Systems introduces The Language of Patterns as a path to systems analysis and modeling. The Language of Patterns is a descriptive modeling language used at each step of the scientific knowledge construction process or Progression of Inquiry. Using these fundamental ideas, the Language of Patterns develops the tools for critical thinking and analysis that underlie all knowledge construction. The Language of Patterns is used to characterize, explore, and understand any system of interest. Scientific inquiry uses the Language of Patterns at every level from observation, through to model building, hypothesis testing, and experimental verification. Critical thinking skills and the process of scientific inquiry are practiced anytime the Language of Patterns is used. This simple text and practice workbook introduces the fundamentals of systems analysis, scientific thinking and critical analysis in a non-technical and easily accessible method. It includes a coherent series of graphical analyzers to guide learning and analysis.