This new edition of Introduction to the Cellular and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic. Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research:

This new edition o Introduction and Molecular Biology of Cancer provides a concise yet comprehensive overview of cancer biology, covering the current status of both research and treatment. For the student or new researcher the breadth of cancer research can appear daunting, yet a broad understanding is essential for translation of laboratory findings into the clinic.
Within the broad scope of the book, each topic is reviewed authoritatively by experts in the field, and the accompanying bibliographies allow rapid access to the relevant current literature. The book covers topics extending from the molecular alterations found in cancer cells and their causes to the current range of approaches to treatment. Since the publication of the previous edition in 1997 there has been unprecedented progress in cancer research: this is reflected by an extensive revision of all the material, and the addition of eight new chapters, covering DNA repair, epigenetic events, the cell cycle, cell immortalization, apoptosis, angiogenesis, animal models, the genome, transcriptome and proteome, radiotherapy and molecular radiotherapy, immunotherapy, and gene therapy. The fourth edition of the popular book will serve as a text for both undergraduate and postgraduate use and also as an introduction for clinicians and scientists new to the field.

This is a textbook for health professionals on the topic of tobacco reduction and cessation.

This revised edition of Methadone Maintenance: A Physician's Guide to Treatment reflects substantial updates to the previous 1998 version and is consistent with the 2001 College of Physicians and Surgeons of Ontario Methadone Maintenance Guidelines. This book provides guidance on methadone prescribing and dispensing, and includes essential information on such topics as: - methadone dose tapering - drug interactions involving methadone - using methadone in opioid withdrawal management - managing pain in patients being treated with methadone - managing pregnancy in women in methadone maintenance treatment.

There have been impressive improvements in the diagnosis and treatment of cancer in recent decades. In economically advantaged countries with well-developed healthcare systems over 50% of all cancer patients achieve long term survival and are probably cured. Not only has survival improved radically for cancer patients but also there has been an increasing focus on the quality of patient's lives, on improving the patient experience of care and on developing effective support for the very many cancer survivors. Despite the progress in cancer treatment, unfortunately a substantial number of cancer patients will still ultimately die of their disease. For many this will follow periods of successful treatment which results in good remissions and good quality of life. Helping patients to make the right choices about their care towards the end of their lives is one of the greatest and most challenging responsibilities of all healthcare professionals. Legal change on the provision of assisted dying by healthcare professionals has occurred in a substantial number of jurisdictions. This work brings together contributions on end of life choices from experienced professionals from oncology disciplines, palliative care, law, nurses and professions allied to medicine. The goals are: * To better inform cancer care professionals and the wider community about developments in choices in end of life care for cancer patients internationally. * To better answer questions from patients and respond to requests from patients, including questions about and requests for assisted dying in countries where it is legal to do so. * To have a balanced and well informed dialogue about choices available to patients without developing a formal policy position on change in law. * To provide a basis of information for future educational activities.