This book constitutes the thoroughly refereed short papers, workshops and doctoral consortium papers of the 22th European Conference on Advances in Databases and Information Systems, ADBIS 2018, held in Budapest, Hungary, in September 2018. The 20 full and the 4 short workshop papers as well as the 3 doctoral consortium papers were carefully reviewed and selected from 54 submissions to the workshops and 6 submissions to the doctoral consortium. Furthermore, there are 10 short papers included, which were accepted for the main conference. The papers are organized according to the 6 workshops and the doctoral consortium: ADBIS 2018 short papers; First Workshop on Advances on Big Data Management, Analytics, Data Privacy and Security, BigDataMAPS 2018; First International Workshop on New Frontiers on Meta-data Management and Usage, M2U 2018; First Citizen Science Applications and Citizen Databases Workshop, CSADB 2018; First International Workshop on Articial Intelligence for Question Answering, AI*QA 2018; First International Workshop on BIG Data Storage, Processing and Mining for Personalized MEDicine, BIGPMED 2018; First Workshop on Current Trends in Contemporary Information Systems and Their Architectures, ISTREND 2018; Doctoral Consortium.