This new edition of the book series dedicated to "Progress in Epileptic Disorders" is the result of a recently held unique gathering of international experts that debated on the prognostic and therapeutic issues raised by the new management of first unprovoked seizures and of newly diagnosed epilepsy. Current knowledge on natural evolution of a first seizure, the role of co-morbid conditions, the impact of immediate versus delayed treatment and recent guidelines are thoroughly addressed. The new ideas and suggestions that emerge from this book offer challenging perspectives for both patient care and clinical as well as fundamental research.

This work is the result of a recently held International Epilepsy Colloquium on the mesial temporal lobe epilepsies (MTLE) which covered all aspects of this specific group of syndromes (or constellations), from animal model to treatment strategies. Written by international experts from different fields, it aims to provide professionals from neuroscientists to clinical neurologists, neurosurgeons and neuropaedia-tricians dealing with mesial temporal lobe epilepsy, with a concise overview on the current body of knowledge and on emerging concepts and findings.