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Many diseases earlier considered to be incurable are now being
treated with modern innovations involving fetal tissue transplants
and stem cells derived from fetal tissues. Fetal tissues are the
richest source of fetal stem cells as well as other varying states
of differentiated cells and support or stromal cells. The activity
of such stem cells is at their peak provided they are given the
correct niche. Stem cells, as we know, are immortal cells with the
capacity to regenerate into any kind of differentiated cell as per
niche-guidance. As such, fetal tissues have the potential capacity
to mend, regenerate and repair damaged cells or tissues in adults,
when directly transplanted to the site of injury, or even when
transplanted in some other site, because it may have a homing
capacity to migrate to the site of the specific injured organ. This
is a new area of translational research and needs to be highlighted
because of its immense potential. This book will bring together the
new work of prominent medical scientists and clinicians who are
conducting pioneering research in human fetal tissue
transplantation. This will include direct transplant of healthy
fetal tissue into mature patients as well as in hosts with genetic
diseases. Transplant techniques, donor-host interaction, cell and
tissue storage, ethical and legal issues, are some of the many
matters which the book will deal with.
Many diseases earlier considered to be incurable are now being
treated with modern innovations involving fetal tissue transplants
and stem cells derived from fetal tissues. Fetal tissues are the
richest source of fetal stem cells as well as other varying states
of differentiated cells and support or stromal cells. The activity
of such stem cells is at their peak provided they are given the
correct niche. Stem cells, as we know, are immortal cells with the
capacity to regenerate into any kind of differentiated cell as per
niche-guidance. As such, fetal tissues have the potential capacity
to mend, regenerate and repair damaged cells or tissues in adults,
when directly transplanted to the site of injury, or even when
transplanted in some other site, because it may have a homing
capacity to migrate to the site of the specific injured organ. This
is a new area of translational research and needs to be highlighted
because of its immense potential. This book will bring together the
new work of prominent medical scientists and clinicians who are
conducting pioneering research in human fetal tissue
transplantation. This will include direct transplant of healthy
fetal tissue into mature patients as well as in hosts with genetic
diseases. Transplant techniques, donor-host interaction, cell and
tissue storage, ethical and legal issues, are some of the many
matters which the book will deal with.
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