This book constitutes the refereed proceedings of the 4th International Workshop on Machine Learning in Medical Imaging, MLMI 2013, held in conjunction with the International Conference on Medical Image Computing and Computer Assisted Intervention, MICCAI 2013, in Nagoya, Japan, in September 2013. The 32 contributions included in this volume were carefully reviewed and selected from 57 submissions. They focus on major trends and challenges in the area of machine learning in medical imaging and aim to identify new cutting-edge techniques and their use in medical imaging.

This book constitutes the refereed proceedings of the Second International Workshop on Machine Learning in Medical Imaging, MLMI 2011, held in conjunction with MICCAI 2011, in Toronto, Canada, in September 2011. The 44 revised full papers presented were carefully reviewed and selected from 74 submissions. The papers focus on major trends in machine learning in medical imaging aiming to identify new cutting-edge techniques and their use in medical imaging.

The first International Workshop on Machine Learning in Medical Imaging, MLMI 2010, was held at the China National Convention Center, Beijing, China on Sept- ber 20, 2010 in conjunction with the International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI) 2010. Machine learning plays an essential role in the medical imaging field, including image segmentation, image registration, computer-aided diagnosis, image fusion, ima- guided therapy, image annotation, and image database retrieval. With advances in me- cal imaging, new imaging modalities, and methodologies such as cone-beam/multi-slice CT, 3D Ultrasound, tomosynthesis, diffusion-weighted MRI, electrical impedance to- graphy, and diffuse optical tomography, new machine-learning algorithms/applications are demanded in the medical imaging field. Single-sample evidence provided by the patient's imaging data is often not sufficient to provide satisfactory performance; the- fore tasks in medical imaging require learning from examples to simulate a physician's prior knowledge of the data. The MLMI 2010 is the first workshop on this topic. The workshop focuses on major trends and challenges in this area, and works to identify new techniques and their use in medical imaging. Our goal is to help advance the scientific research within the broad field of medical imaging and machine learning. The range and level of submission for this year's meeting was of very high quality. Authors were asked to submit full-length papers for review. A total of 38 papers were submitted to the workshop in response to the call for papers.

This book constitutes the proceedings of the 12th International Workshop on Machine Learning in Medical Imaging, MLMI 2021, held in conjunction with MICCAI 2021, in Strasbourg, France, in September 2021.*The 71 papers presented in this volume were carefully reviewed and selected from 92 submissions. They focus on major trends and challenges in the above-mentioned area, aiming to identify new-cutting-edge techniques and their uses in medical imaging. Topics dealt with are: deep learning, generative adversarial learning, ensemble learning, sparse learning, multi-task learning, multi-view learning, manifold learning, and reinforcement learning, with their applications to medical image analysis, computer-aided detection and diagnosis, multi-modality fusion, image reconstruction, image retrieval, cellular image analysis, molecular imaging, digital pathology, etc. *The workshop was held virtually.

This book constitutes the proceedings of the 11th International Workshop on Machine Learning in Medical Imaging, MLMI 2020, held in conjunction with MICCAI 2020, in Lima, Peru, in October 2020. The conference was held virtually due to the COVID-19 pandemic. The 68 papers presented in this volume were carefully reviewed and selected from 101 submissions. They focus on major trends and challenges in the above-mentioned area, aiming to identify new-cutting-edge techniques and their uses in medical imaging. Topics dealt with are: deep learning, generative adversarial learning, ensemble learning, sparse learning, multi-task learning, multi-view learning, manifold learning, and reinforcement learning, with their applications to medical image analysis, computer-aided detection and diagnosis, multi-modality fusion, image reconstruction, image retrieval, cellular image analysis, molecular imaging, digital pathology, etc.

This book constitutes the proceedings of the 10th International Workshop on Machine Learning in Medical Imaging, MLMI 2019, held in conjunction with MICCAI 2019, in Shenzhen, China, in October 2019. The 78 papers presented in this volume were carefully reviewed and selected from 158 submissions. They focus on major trends and challenges in the area, aiming to identify new-cutting-edge techniques and their uses in medical imaging. Topics dealt with are: deep learning, generative adversarial learning, ensemble learning, sparse learning, multi-task learning, multi-view learning, manifold learning, and reinforcement learning, with their applications to medical image analysis, computer-aided detection and diagnosis, multi-modality fusion, image reconstruction, image retrieval, cellular image analysis, molecular imaging, digital pathology, etc.

This book constitutes the refereed proceedings of the Third International Workshop on Machine Learning in Medical Imaging, MLMI 2012, held in conjunction with MICCAI 2012, in Nice, France, in October 2012. The 33 revised full papers presented were carefully reviewed and selected from 67 submissions. The main aim of this workshop is to help advance the scientific research within the broad field of machine learning in medical imaging. It focuses on major trends and challenges in this area, and it presents work aimed to identify new cutting-edge techniques and their use in medical imaging.