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The synthesis of chalcone system -C=C-C=O is relatively easy to
prepare, usually highly reactive and are starting point of
preparation of various bioactive compounds. This, -unsaturated
ketones (chalcones) can be synthesized by Claisen-Schmidt
condensation of different aromatic aldehydes with ketone and their
cyclization with hydrazine hydrate in basic condition. Numerous
pyrazoline derivatives have been found to possess considerable
biological activities, which stimulated the research activity in
this field. Amongst all the nitrogen containing five member
heterocycles, it have proved to be the most useful framework for
biological activities and have attracted attention of medicinal
chemists for both with regard to heterocyclic chemistry and the
pharmacological activities associated with them. We have
synhtesized some chalcones and pyrazolines and have studied their
antimicrobial activity.
The nanosciences have recently evolved as a major research
direction of our modern Society resulting from an ongoing effort to
miniaturize at the nanoscale processes that currently use
microsystems. Towards this end, it is well admitted that the bottom
- up approach should now replace the classic top - down one, a
strategic move that is common to several areas of nanosciences
including opto - electronics, sensing, medicine and catalysis . The
latter discipline certainly is the key one for the development of
starting chemicals, fine chemicals and drugs from raw materials.
Exciting new opportunities are emerging in the field of catalysis
based on nanotechnology approaches. A new understanding and mastery
of catalysis could have broad societal impacts, since about 80% of
the processes in the chemical industry depend on catalysts to work
efficiently. Efforts in surface science have led to the discovery
of new heterogeneous catalysts.
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