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This book presents a collection of articles on various aspects of
current research on aging. These include model systems, cellular,
biochemical and molecular aspects of experimental aging research,
as well as selected intervention studies on age-related diseases.
Aging is a global challenge to human society. Children are always
in a hurry to become adults, while adults produce offspring and add
to the gene pool. However, after adulthood or the attainment of
reproductive maturity, all physiological parameters of the living
organism start to undergo the aging process. Old age sets in slowly
but surely, and usually continues for a prolonged period. If vigor
and vitality are the main advantages of adulthood, old age offers
the rewards of experience and maturity. Biologists ask questions
such as: Why do we age? How do we become old? Is it possible to
slow down, postpone or even prevent aging? In turn, medical experts
ask: What are the diseases associated with old age? Are there
medicines that can help affected elderly patients? In fact both
groups are asking themselves how can we add more health to old age.
Healthy aging is the dream of every individual. But to achieve
this, it is fundamental that we first understand the cellular,
biochemical and molecular basis of the aging process in mammalian
cells, tissues and intact living organisms, which can serve as
experimental model systems in Biomedical Gerontology. Once the
biology of aging is understood at the genetic and molecular levels,
interventional approaches to aging and its associated diseases may
be easier to plan and implement at the preclinical level.
This book examines the basic cellular and molecular mechanisms
associated with aging. It comprehensively describes the genetic,
epigenetic, biochemical and metabolic regulation of aging, as well
as some important age-related diseases. Divided into two major
sections, it takes readers through the various aspects of aging in
a story-like manner and suggests various interventions for healthy
aging, such as dietary restriction, regular exercise, nutrition and
maintaining a balanced and a non-stressful lifestyle. It describes
the implications of aging on the nervous system, metabolism,
immunity and stem cells as well as care for the elderly. The book
is an ideal companion for both new and established researchers in
the field and is also useful for educators, clinicians and policy
makers.
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