This book constitutes the refereed proceedings of the 5th Annual Smart City 360 Degrees Summit, held in Braga, Portugal, in December 2019. The volume combines selected papers of four conferences, namely IoT in Urban Space, Urb-IoT 2019, Smart Governance for Sustainable Smart Cities, SmartGov 2019, Sensor Systems and Software, S-Cube 2019, and Intelligent Technologies for Interactive Entertainment, Intetain 2019. The 5 keynote and 32 conference papers presented were carefully reviewed and selected from 113 submissions and present results of multidisciplinary scientific and industry collaboration to solve complex societal, technological and economic problems Smart Cities. As such, the main goals are to promote quality of life, work conditions, mobility and sustainability.