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Lipid Mediators in the Immunology of Shock (Paperback, Softcover Repri): M. Paubert-Braquet, P. Braquet, B. Demling, R.... Lipid Mediators in the Immunology of Shock (Paperback, Softcover Repri)
M. Paubert-Braquet, P. Braquet, B. Demling, R. Fletcher, M. Foegh
R1,657 Discovery Miles 16 570 Ships in 10 - 15 working days

This book contains the proceedings of the ARW NATO conference on Lipid Mediators in Immunology of Burn and Sepsis held in He1singor, Denmark, July 20-25, 1986. This meeting brought together some of the most distinguished re- searchers in the fields of thermal injury, the immune system and lipid mediator biochemistry. It is well known that there is a substantial impairment of the immune response during sepsis, burn, trauma and other kinds of shock. These conditions are characterized by a massive inflammatory process which occurs during the early phase following injury. Among the various mediators released at this time are 1euko- trienes, thromboxane, histamine and platelet-activating factor. This latter autocoid possesses potent proinf1ammatory properties and toge- ther with the other mediators may account for some of the post-injury pathophysi 01 ogi ca 1 phenomena such as extravasati on, hypotensi on, chemotaxis...It is of great interest to note that recently 1euko- tri enes and plate 1 et-acti vati ng factor have been shown to be potent mediators of the immune response. Thus, the purpose of this meeting was to bring together clinicians, immunologists and biochemists in order to examine and hopefully clarify the putative role of various lipid mediators prominent in the early stages after injury. This book is divided into the following six sections. Section 1 provides a general overview of the physiological con- sequences of burn, sepsis and shock.

Practical Methods of Optimization 2e (Paperback, 2nd Edition): R. Fletcher Practical Methods of Optimization 2e (Paperback, 2nd Edition)
R. Fletcher
R2,248 Discovery Miles 22 480 Ships in 12 - 17 working days

This established textbook is noted for its coverage of optimization methods that are of practical importance. It provides a thorough treatment of standard methods such as linear and quadratic programming, Newton-like methods and the conjugate gradient method. The theoretical aspects of the subject include an extended treatment of optimality conditions and the significance of Lagrange multipliers. The relevance of convexity theory to optimization is also not neglected. A significant proportion of the book is devoted to the solution of nonlinear problems, with an authoritative treatment of current methodology. Thus state of the art techniques such as the BFGS method, trust region methods and the SQP method are described and analysed. Other features are an extensive treatment of nonsmooth optimization and the L1 penalty function. Contents Part 1 Unconstrained Optimization Part 2 Constrained Optimization

  1. Introduction
  2. Structure of Methods
  3. Newton-like Methods
  4. Conjugate Direction Methods
  5. Restricted Step Methods
  6. Sums of Squares and Nonlinear Equations
  7. Introduction
  8. Linear Programming
  9. The Theory of Constrained Optimization
  10. Quadratic Programming
  11. General Linearly Constrained Optimization
  12. Nonlinear Programming
  13. Other Optimization Problems
The 21st Century Industrial Robot: When Tools Become Collaborators (Paperback, 1st ed. 2022): Maria Isabel Aldinhas Ferreira,... The 21st Century Industrial Robot: When Tools Become Collaborators (Paperback, 1st ed. 2022)
Maria Isabel Aldinhas Ferreira, Sarah R. Fletcher
R4,486 Discovery Miles 44 860 Ships in 10 - 15 working days

This book aims to discuss the technical and ethical challenges posed by the present technological framework and to highlight the fundamental role played by human-centred design and human factors in the definition of robotic architectures for human-robot collaboration. The book gives an updated overview of the most recent robotic technology, conceived and designed to collaborate with human beings in industrial working scenarios. The technological development of robotics over the last years and the fast evolution of AI, machine learning and IoT have paved the way for applications that extend far beyond the typical use of robots performing repetitive tasks in exclusive spaces. In this new technological paradigm that is expected to drive the robotics market in the coming years, robots and workers will coexist in the same workplace, sharing not only this lived space, but also the roles and functions inherent to a process of production, merging the benefits of automated and manual performing. However, having robots cooperating in real time with workers, responding in a physical, psychological and social adequate way, requires a human-centred design that not only calls for high safety standards regulating the quality of human-robot interaction, but also demands the robot's fine-grained perception and awareness of the dynamics of its surrounding environment, namely the behaviours of their human peers-their expected actions/responses-fostering the necessary collaborative efforts towards the accomplishment of the tasks to be executed.

Beyond Redemption (Paperback): Michael R. Fletcher Beyond Redemption (Paperback)
Michael R. Fletcher
R382 R245 Discovery Miles 2 450 Save R137 (36%) Ships in 12 - 17 working days

A darkly imaginative writer in the tradition of Joe Abercrombie, Peter V. Brett, and Neil Gaiman conjures a gritty mind-bending fantasy, set in a world where delusion becomes reality ...and the fulfillment of humanity's desires may well prove to be its undoing. When belief defines reality, those with the strongest convictions-the crazy, the obsessive, the delusional-have the power to shape the world. And someone is just mad enough to believe he can create a god ...Violent and dark, the world is filled with the Geisteskranken-men and women whose delusions manifest. Sustained by their own belief-and the beliefs of those around them-they can manipulate their surroundings. For the High Priest Konig, that means creating order out of the chaos in his city-state, leading his believers to focus on one thing: helping a young man, Morgen, ascend to become a god. A god they can control. Trouble is, there are many who would see a god in their thrall, including the High Priest's own doppelgangers, a Slaver no one can resist, and three slaves led by possibly the only sane man left. As these forces converge on the boy, there's one more obstacle: time is running out. Because as the delusions become more powerful, the also become harder to control. The fate of the Geisteskranken is to inevitably find oneself in the Afterdeath. The question, then, is: Who will rule there?

The 21st Century Industrial Robot: When Tools Become Collaborators (Hardcover, 1st ed. 2022): Maria Isabel Aldinhas Ferreira,... The 21st Century Industrial Robot: When Tools Become Collaborators (Hardcover, 1st ed. 2022)
Maria Isabel Aldinhas Ferreira, Sarah R. Fletcher
R4,519 Discovery Miles 45 190 Ships in 10 - 15 working days

This book aims to discuss the technical and ethical challenges posed by the present technological framework and to highlight the fundamental role played by human-centred design and human factors in the definition of robotic architectures for human-robot collaboration. The book gives an updated overview of the most recent robotic technology, conceived and designed to collaborate with human beings in industrial working scenarios. The technological development of robotics over the last years and the fast evolution of AI, machine learning and IoT have paved the way for applications that extend far beyond the typical use of robots performing repetitive tasks in exclusive spaces. In this new technological paradigm that is expected to drive the robotics market in the coming years, robots and workers will coexist in the same workplace, sharing not only this lived space, but also the roles and functions inherent to a process of production, merging the benefits of automated and manual performing. However, having robots cooperating in real time with workers, responding in a physical, psychological and social adequate way, requires a human-centred design that not only calls for high safety standards regulating the quality of human-robot interaction, but also demands the robot's fine-grained perception and awareness of the dynamics of its surrounding environment, namely the behaviours of their human peers-their expected actions/responses-fostering the necessary collaborative efforts towards the accomplishment of the tasks to be executed.

The Peach Tree. How to Plant, Grow, Prune and Cultivate Successfully on New England Soil (Hardcover): Rufus R. Fletcher The Peach Tree. How to Plant, Grow, Prune and Cultivate Successfully on New England Soil (Hardcover)
Rufus R. Fletcher
R722 Discovery Miles 7 220 Ships in 10 - 15 working days
The Peach Tree. How to Plant, Grow, Prune and Cultivate Successfully on New England Soil: Rufus R. Fletcher The Peach Tree. How to Plant, Grow, Prune and Cultivate Successfully on New England Soil
Rufus R. Fletcher
R366 Discovery Miles 3 660 Ships in 10 - 15 working days
The Drake Effect (Paperback): Richard J Fletcher The Drake Effect (Paperback)
Richard J Fletcher; Illustrated by James a Fletcher; Louis R Fletcher
R242 Discovery Miles 2 420 Ships in 10 - 15 working days
My First Hundred Years (Hardcover): Donald R. Fletcher My First Hundred Years (Hardcover)
Donald R. Fletcher
R960 R776 Discovery Miles 7 760 Save R184 (19%) Ships in 10 - 15 working days
Mute of Malice (Paperback): James a Fletcher Mute of Malice (Paperback)
James a Fletcher; Edited by Richard J Fletcher; Louis R Fletcher
R241 Discovery Miles 2 410 Ships in 10 - 15 working days
My First Hundred Years (Paperback): Donald R. Fletcher My First Hundred Years (Paperback)
Donald R. Fletcher
R548 R451 Discovery Miles 4 510 Save R97 (18%) Ships in 10 - 15 working days
Dialogues with Jen (Paperback): Donald R. Fletcher Dialogues with Jen (Paperback)
Donald R. Fletcher
R303 R246 Discovery Miles 2 460 Save R57 (19%) Ships in 10 - 15 working days
Dialogues with Jen (Hardcover): Donald R. Fletcher Dialogues with Jen (Hardcover)
Donald R. Fletcher
R796 R643 Discovery Miles 6 430 Save R153 (19%) Ships in 10 - 15 working days
A Collection of Obsessions - The Short Stories of Michael R. Fletcher (Paperback): Anna Smith Spark A Collection of Obsessions - The Short Stories of Michael R. Fletcher (Paperback)
Anna Smith Spark; Michael R. Fletcher
R366 Discovery Miles 3 660 Ships in 10 - 15 working days
Dialogues with Jay (Paperback): Donald R. Fletcher Dialogues with Jay (Paperback)
Donald R. Fletcher
R350 R283 Discovery Miles 2 830 Save R67 (19%) Ships in 10 - 15 working days
Dialogues with Jay (Hardcover): Donald R. Fletcher Dialogues with Jay (Hardcover)
Donald R. Fletcher
R845 R681 Discovery Miles 6 810 Save R164 (19%) Ships in 10 - 15 working days
By Scalpel and Cross (Paperback): Donald R. Fletcher By Scalpel and Cross (Paperback)
Donald R. Fletcher; Foreword by Sung-Deuk Oak
R780 R640 Discovery Miles 6 400 Save R140 (18%) Ships in 10 - 15 working days
By Scalpel and Cross (Hardcover): Donald R. Fletcher By Scalpel and Cross (Hardcover)
Donald R. Fletcher; Foreword by Sung-Deuk Oak
R1,285 R1,015 Discovery Miles 10 150 Save R270 (21%) Ships in 10 - 15 working days
Martha and I - Life, Love, and Loss in Alzheimer's Shadow (Paperback): Donald R. Fletcher Martha and I - Life, Love, and Loss in Alzheimer's Shadow (Paperback)
Donald R. Fletcher
R784 R637 Discovery Miles 6 370 Save R147 (19%) Ships in 10 - 15 working days
Martha and I (Hardcover): Donald R. Fletcher Martha and I (Hardcover)
Donald R. Fletcher
R1,285 R1,008 Discovery Miles 10 080 Save R277 (22%) Ships in 10 - 15 working days
Real Food (Paperback): Michael R. Fletcher Real Food (Paperback)
Michael R. Fletcher
R294 Discovery Miles 2 940 Ships in 10 - 15 working days
The Gift - Looking to Jesus as He Was (Paperback): Donald R. Fletcher The Gift - Looking to Jesus as He Was (Paperback)
Donald R. Fletcher
R355 Discovery Miles 3 550 Ships in 10 - 15 working days

The book opens with a parable: On Christmas morning one gift remains, beautiful and complex, given to all the family, but with no manual to tell how to put it together. Jesus, the Gift, comes with no divinely dictated instruction to say what his brief life and his message mean; so that, from the beginning, his followers have been offering their interpretations, sometimes sharply disagreeing. This author, with a lifetime perspective, examines and sifts together what the three synoptists, Mark, Matthew and Luke, record as remembered sayings of Jesus, listening for those moments when the Gift's own voice seems to come through.

Air Force Bases - Air Bases Outside the United States of America (Paperback): Center for Air Force History, Harry R Fletcher Air Force Bases - Air Bases Outside the United States of America (Paperback)
Center for Air Force History, Harry R Fletcher
R724 Discovery Miles 7 240 Ships in 10 - 15 working days

This volume is the second in a series on active Air Force bases and a continuation of a recent line of works prepared for the Center for Air Force History under the Reference Series. These reference books contain specific information about a number of topics of interest to the United States Air Force and other arms of the Department of Defense. This Volume II in the Air Force Bases series provides important background information about overseas installations that are less well known than domestic stations.

Turnings - Lyric Poems Along a Road (Paperback): Donald R. Fletcher Turnings - Lyric Poems Along a Road (Paperback)
Donald R. Fletcher
R455 R405 Discovery Miles 4 050 Save R50 (11%) Ships in 10 - 15 working days


One Man's Inspiring Journey of Vision and Service
Part memoir and part anthology-this book is a spiritual autobiography. Don describes in vivid scenes the road he has taken through a long life and the epiphanies that have come to him along the turnings of that road. And because he has a gift of lyric poetry, he includes a rich selection of poems written as his life experience unfolds, marking the evolving of a sensitive spirit.

Turnings - Lyric Poems Along a Road (Hardcover): Donald R. Fletcher Turnings - Lyric Poems Along a Road (Hardcover)
Donald R. Fletcher
R843 R734 Discovery Miles 7 340 Save R109 (13%) Ships in 10 - 15 working days


One Man's Inspiring Journey of Vision and Service
Part memoir and part anthology-this book is a spiritual autobiography. Don describes in vivid scenes the road he has taken through a long life and the epiphanies that have come to him along the turnings of that road. And because he has a gift of lyric poetry, he includes a rich selection of poems written as his life experience unfolds, marking the evolving of a sensitive spirit.

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