|
Showing 1 - 1 of
1 matches in All Departments
Strychnine and picrotoxin were tested as possible antagonists of
two puta- tive inhibitory transmitters in the retina: taurine and
GABA, Strychnine was shown to antagonize the depressive action of
taurine on the ERG b-wave, but it did not affect the depressive
action of GABA. Conversely, picrotoxin had no effect on the
depressive action of taurine on the ERG b-wave, but it antagonizes
to some extent the depressive effect of GABA. These data, as well
as those obtained through recording tectal evoked responses, lead
to the conclusion that taurine and GABA do not act in the same way
in retinal inhibitory synaptic transmission. REFERENCES CURTIS,
D.R., AW. DUGGAN & G.A.R. JOflNSTON. Glycine, strychnine,
picro- toxine and spinal inhibition. Brain Res. 14, 759-762 (1969).
CURTIS, D.R., L. HOSLI & G.AR. JOHNSTON. A pharmacological
study of the depression of spinal neurones by glycine and related
aminoacids. Exp. Brain Res. 6, 1-18 (1968 a). CURTIS, D.R.,
L.HOSLI, G.A.R. JOHNSTON & LH. JOHNSTON. The hyperpolariza-
tion of spinal motoneurones by glycine and related aminoacids. Exp.
Brain Res. 5, 235-258 (1968 b). CURTIS, D.R. & A.K. TEBECIS.
Bicuculline and thalamic inhibition. Exp. Brain Res. 16,210-218
(1972). DA VIDSON, N. & H. REISINE. Presynaptic inhibition in
cuneate blocked by GABA antagonists. Nature New Biology 234,223-224
(1971).
|
You may like...
Loot
Nadine Gordimer
Paperback
(2)
R205
R164
Discovery Miles 1 640
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.