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The development and selection of ovarian follicles is one of the
most active areas of contemporary reproductive research. Relevant
experimental work extends from laboratory rodents, across a wide
range of domestic species, to human clinical studies, especially as
related to problems of fertility and in vitro fertilisation. This
2003 volume provides comprehensive coverage of the field,
integrating research findings from animal and human studies and
condensing the vast published literature into a meaningful and
digestible physiological account which highlights the key role
played by the oocyte in influencing all stages of follicular
development.
How do males become male and females become female? And what are
the consequences if the decision is not incisive? Drawing upon
interests in animal genetics and molecular biology, the author
endeavours to answer these difficult yet fascinating questions.
Originally published in 1995, this book describes the genetic
determination of sex and examines how sexual organs are
differentiated. Using examples of intersexuality, chimaeras and
asymmetries, the book describes the underlying molecular basis of
sex determination and sexual differentiation, and focuses on the
critical role of the rate of embryonic development in these vital
processes. Male precocity is a recurrent theme, as is the
involvement of Sertoli cells and their secretion of anti-Mullerian
hormone. An invaluable book for reproductive physiologists,
geneticists and developmental biologists whose interests may extend
from animal science through veterinary medicine to human clinical
medicine.
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