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I welcome the privilege of writing some words of introduction to
this important book. Its authors have been courageous in bringing
together in one text a triad of topics that cover such large tracts
of biomedical sciences as epidemiology, biochemistry, immunology,
and clinical medicine. Malnutrition and infection are known to be
closely linked, the one promoting the other. The adaptive immune
system forms a part of the link since it is responsible for a good
deal of defense against infection, and it may be affected adversely
by malnutrition and indeed by infection itself. Knowledge in this
complex field is of great potential importance because malnutri
tion and infection are such dominant features of the ill-health of
many of the world's underprivileged people. As this book shows,
there is no lack of technical facets for study. There are now so
many components of the immune response which can be measured or
assessed and so many aspects of nutritional biochemistry which can
be studied that the problem is to select what to study and where to
begin. Moreover, the great number of variables in the nature of
nutritional deficiencies, in types of infections or multiple
infections and in the genetic, environmental, and social background
of the affected people, all combine to make interpretation and
application of findings a speculative business. Descriptions of
cause and effect must us ually be provisional rather than
definitive.
Numerous economic, sociocultural, and health problems continue to
impede the optimal progress of many millions of people in the
developing countries in tropical and other geographic regions of
the world. Thus, tropical medicine has many aspects including
parasitology, bacteriology, and virology, environmental sanitation
and hygiene, nutrition, pharmacology, immunology, agriculture, eco
nomics, political science, anthropology, sociology, and behavioral
sciences. Like the mythical Proteus, the individual dealing with
tropical medicine must assume many roles. There is a growing
recognition of the unique problems of the tropical countries. This
has led to concerted efforts by many international agencies to
attempt to obtain new tools to control many of the tropical
diseases that have defied previous attempts at large-scale control.
The involvement of the world's leading scientists and institutions
as well as the best talents and resources of the developing
countries themselves has inspired considerable research in tropical
medicine with an inevitable exponential growth in publications. The
new series Critical Reviews in Tropical Medicine is being launched
to provide topical state of-the-art critiques of selected subjects
in this burgeoning field. Authored by active investigators in their
chosen topics, these reviews should be useful for all health
professionals, social scientists, and administrators involved in
planning interventions, both preventive and therapeutic, in
developing regions of the world. Contributions included in Volume 1
span parasitology, infectious disease, immunology,
gastroenterology, liver disease, and nutrition."
At the present time there are renewed global efforts to control the
major tropical infections and to stem the tide of malnutrition, the
two serious, often intertwined, problems that contribute to much of
the morbidity and mortality in under privileged populations. Many
international organizations have joined hands with national
governments and with the private sector to search for new
approaches to problems that beset much of the developing world,
including countries in the tropical region. This volume continues
the tradition of the previous publication in the Series. A variety
of fare is offered to readers: explanations of the activities and
achievements of the UNDP/World Bank/WHO Special Programme for Re
search and Training in Tropical Diseases; and studies of infant
mortality, schistosomiasis, trypanosomiasis, helminths, lactase
deficiency, oral rehydration therapy, functional consequences of
iron deficiency, and fertility control. Au thoritative
state-of-the-art reviews provide a critical analysis of recent
data. I hope the Series will continue to prove useful to all those
working in the tropics and to those in the industrialized countries
whose awareness of physical health problems of the Third World is
relatively limited. R. K. Chandra St. John's, Newfoundland VlI
Contents Chapter 1. The Special Programme for Research and Training
in Tropical Diseases . . . . . . . . . . . . . . . . . . . DAVID S.
ROWE 1. Origins, Objectives, and Diseases. . . . . . . . . . . . .
. . . . . . . . . . . . . . 1 2. The Modus Operandi of the
Programme. . . . . . . . . . . . . . . . . . . . . . 3 2. 1.
Scientific Working Groups. . . . . . . . . . . . . . . . . . . . .
. . . . . . . 3 2. 2. Research Strengthening Group. . . . . . . . .
. . . . . . . . . . . . . . . . 7 2. 3. The Scientific and
Technical Advisory Committee. . . . . . . . . 7 2. 4. Joint
Coordinating Board. . . . . . . . . . . . . . . . . . . . . . . . .
. . . ."
At the present time there are renewed global efforts to control the
major tropical infections and to stem the tide of malnutrition, the
two serious, often intertwined, problems that contribute to much of
the morbidity and mortality in under- privileged populations. Many
international organizations have joined hands with national
governments and with the private sector to search for new
approaches to problems that beset much of the developing world,
including countries in the tropical region. This volume continues
the tradition of the previous publication in the Series. A variety
of fare is offered to readers: explanations of the activities and
achievements of the UNDP/World Bank/WHO Special Programme for Re-
search and Training in Tropical Diseases; and studies of infant
mortality, schistosomiasis, trypanosomiasis, helminths, lactase
deficiency, oral rehydration therapy, functional consequences of
iron deficiency, and fertility control. Au- thoritative
state-of-the-art reviews provide a critical analysis of recent
data. I hope the Series will continue to prove useful to all those
working in the tropics and to those in the industrialized countries
whose awareness of physical health problems of the Third World is
relatively limited. R. K. Chandra St. John's, Newfoundland VlI
Contents Chapter 1. The Special Programme for Research and Training
in Tropical Diseases . . . . . . . . . . . . . . . . . . . DAVID S.
ROWE 1. Origins, Objectives, and Diseases. . . . . . . . . . . . .
. . . . . . . . . . . . . . 1 2. The Modus Operandi of the
Programme. . . . . . . . . . . . . . . . . . . . . . 3 2. 1.
Scientific Working Groups. . . . . . . . . . . . . . . . . . . . .
. . . . . . . 3 2. 2. Research Strengthening Group. . . . . . . . .
. . . . . . . . . . . . . . . . 7 2. 3. The Scientific and
Technical Advisory Committee. . . . . . . . . 7 2. 4. Joint
Coordinating Board. . . . . . . . . . . . . . . . . . . . . . . . .
. . . .
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