Octavia E. Butler is widely recognized today as one of the most important figures in contemporary science fiction. Bringing together leading and emerging scholars and covering Butler’s complete works from the bestselling novel Kindred, to her short stories and major novel sequences Patternmaster, Xenogenesis and The Parables, this is the most comprehensive Companion to Butler scholarship available today. The Bloomsbury Handbook to Octavia E. Butler covers the full range of contemporary scholarly themes and approaches to the author’s work, including: · Cyborgs and the posthuman · Race and African American history · Afrofuturism · Gender and sexuality · New perspectives from Religious Studies, the Environmental Humanities and Disability Studies · New discoveries from the Butler archives at the Huntington Library The book includes a comprehensive bibliography of works by Butler and secondary scholarship on her work as well as an afterword by the novelist Tananarive Due.

When a problem arises with a product regulated by FDA, the Agency can take a number of actions to protect the public health. Initially, the agency works with the manufacturer to correct the problem voluntarily. If that fails, administrative enforcement and legal remedies include asking the manufacturer to recall a product and having federal marshals seize products if a voluntary recall is not done. Drugs can be seized and medical devices can be detained and imports can be stopped at the port of entry until problems are corrected. If warranted, FDA can ask the courts to issue injunctions or prosecute those that deliberately violate the law. When warranted, criminal penalties-including prison sentences-are sought. Ensuring that your company is in compliance at all times in all departments is a never-ending task. Failure to get it right, even once, can mean excessive fines, penalties, or possible debarment. The FDA Administrative Enforcement Manual explores the control of drug research in pharmaceutical, vaccine, biologic, biotechnology, medical device, and cosmeceutical industries. Introducing basic industry techniques, the author explores every day industry problems and presents suggested methods for applying the theory to resolve them. The book covers the ten critical Administrative Enforcement areas, including recalls, application integrity, injunctions, seizures, and more. It supplements these topics with regulations, lawsuit case studies, enforcement information, and reference materials. Offering insight into the impact of FDA enforcement on the national and international pharmaceutical industry, practitioners and industry suppliers, the book provides an understanding of drug development and manufacturing regulations in the United States and shows you what it takes to keep your company in compliance. The only complete, single source available, the FDA Administrative Enforcement Manual draws on the author's experience in the trenches of the pharmaceutical industry with administrative enforcement activities.

This book explores an innovative study of women who undergo cosmetic study and the doctors who carry it out. It situates cosmetic surgery as a personal choice made by women against the social and cultural reality of the way women's bodies are scrutinised in Western countries.

This book explores an innovative study of women who undergo cosmetic study and the doctors who carry it out. It situates cosmetic surgery as a personal choice made by women against the social and cultural reality of the way womens bodies are scrutinised in Western countries.

The author discusses whether time travel is scientifically possible. He examines "the history of the development of general relativity, the conceptof curved space-time and the early evolution of the universe. The remainder of the book seeks to] explain the problems that arise when we attempt to turntheoretical holes in space-time into time machines." (N Y Times Book Review)

I remember once watching a presentation of the creation of the universe in a planetarium. It was a fascinating experience: lights flashing, particles appearing to rush by as an explosive roar echoed throughout the planetarium. Then suddenly ... black ness. And after a few seconds ... tiny lights--stars blinking into existence. I tried to imagine myself actually going back to this event. Was this really what it was like? It was an interesting facsimile, but far from what the real thing would have been like. The creation of the universe is an event that is impossible to imagine accurately. Fortunately, this has not discouraged peo ple from wondering what it was like. In Creation I have attempted to take you back to the begin ning-the big bang explosion-so that you can watch the uni verse grow and evolve. Starting with the first fraction of a sec ond, I trace the universe from its initial dramatic expansion through to the formation of the first nuclei and atoms. From here I go to the formation of galaxies and the curious distribu tion they have taken in space. Finally I talk about the formation of elements in stars, and the first life on the planets around them.

By analyzing how America’s greatest presidents displayed their mastery of statecraft, American Presidents in Diplomacy and War offers important lessons about the most effective uses of national power abroad. American Presidents in Diplomacy and War chronicles the major foreign policy crises faced by twelve American presidents in order to uncover the reoccurring patterns of successful and less successful uses of diplomatic, economic, and military power. In this brief and highly readable book, Thomas Parker reveals how America’s most successful leaders manage events instead of allowing events to control them. Parker explores how the U.S. presidency, from the days of the early Republic to the present, shaped the world. Ranging from George Washington to George H. W. Bush, Parker shows how successful statecraft requires the understanding of complex situations, the prudent evaluation of various courses of action, the ability to adapt and to anticipate, and personal determination. Parker compares each of these leaders to their contemporaries—reasonable political leaders who nonetheless made serious mistakes, such as Thomas Jefferson and Barack Obama—to examine the dangers of being unable to strike the right balance of aggressiveness and caution and to examine the costs of inexperience and ambivalence toward military power. The book concludes by discussing the increasingly complex international situation of today, particularly the manifold challenges posed by China and Russia to U.S. foreign policy, and the continued necessity of effective statecraft.

Octavia E. Butler is widely recognized today as one of the most important figures in contemporary science fiction. Bringing together leading and emerging scholars and covering Butler's complete works from the bestselling novel Kindred, to her short stories and major novel sequences Patternmaster, Xenogenesis and The Parables, this is the most comprehensive Companion to Butler scholarship available today. The Bloomsbury Handbook to Octavia E. Butler covers the full range of contemporary scholarly themes and approaches to the author's work, including: * Cyborgs and the posthuman * Race and African American history * Afrofuturism * Gender and sexuality * New perspectives from Religious Studies, the Environmental Humanities and Disability Studies * New discoveries from the Butler archives at the Huntington Library The book includes a comprehensive bibliography of works by Butler and secondary scholarship on her work as well as an afterword by the novelist Tananarive Due.

Contrary to what news reports might suggest, the majority of politicians behave ethically and are never subject to investigations. Is this because of the elaborate system of rules Congress has constructed to regulate the conduct of its members as well as the fear of electoral reprisal? Drawing on economic literature on the behavior of firms, Glenn Parker answers no. He argues that members of Congress behave ethnically not because of the fear of punishment but because of their concern for their reputations. He draws parallels between politicians and businesses, since both stand to suffer significantly when accused of wrongdoing.

Just as business' poor behavior can cause brand names to be tarnished, prices to plummet, and future business to disappear, dishonest politicians stand to sacrifice the human capital invested in their careers, and premiums for honesty, such as electoral security and prestigious post-elective employment. Parker explores public attitudes toward the behavior of members of Congress and shows how those attitudes shape the way members conduct their professional lives. Written from the perspective of public choice, this book offers a novel approach to the question of how to keep politicians honest.

This book is an introduction to programming concepts that uses Python 3 as the target language. It follows a practical just in time presentation - material is given to the student when it is needed. Many examples will be based on games because Python has become the language of choice for basic game development. Designed as a year 1 textbook for introduction to programming classes or for the hobbyist who wants to learn the fundamentals of programming, the text assumes no programming experience. FEATURES: Introduces programming concepts using Python 3. Covers basic computer concepts such as loops, strings, functions, files, graphics, multimedia, algorithms, classes, writing code, etc. Develops graphics, exercises, and user interface using Pygame. Includes many examples based on video game development. 4 color throughout with game demos on the companion files. New chapters on parsing (14) and graphics (15). Instructor ancillaries for use as a textbook.

This book is an introduction to programming concepts that uses Python 3 as the target language. It follows a practical just-in-time presentation - material is given to the student when it is needed. Many examples will be based on games, because Python has become the language of choice for basic game development. Designed as a Year One textbook for introduction to programming classes or for the hobbyist who wants to learn the fundamentals of programming, the text assumes no programming experience. Features: Introduces programming concepts that use Python 3 Includes many examples based on video game development 4-color throughout with game demos on the companion files

The crisis of Spartan power in the first half of the fourth century has been connected to Spartan inability to manage the hegemony built on the ruins of the Athenian Empire, or interpreted as a result of the unexpected annihilation of the Spartan army by the Boeotians at Leuktra. The present book offers a new perspective, suggesting that the crisis that finally brought down Sparta was in important ways a result of centrifugal impulses within the Peloponnesian League, accompanied by a general awakening of ethnicity in various areas of the Peloponnese.

A series of regional case studies is combined with thematic contributions focusing on topics such as the relationship of religious cults and ethnicity and of democracy and ethnicity, the use of archaeological evidence for ethnic phenomena, and comparative approaches based on social anthropology.