|
Showing 1 - 4 of
4 matches in All Departments
Offering a description of current and recently developed laboratory
assays in the field of haemostasis and thrombosis, this work is the
result of a co-operation between experts from more than 60
institutes in 12 European countries, brought together by the ECAT
(European Concerted Action on Thrombosis and Disabilities) under
the auspices of the Commission of the European Communities in
Brussels. The work is based on two previous editions, which were
for internal use only. Each assay was assessed by an expert who
functioned in the ECAT as representative of a reference laboratory.
An assay committee co-ordinated the activities, and each chapter is
written by an assay expert. Most of the chapters give descriptions
of the assay recommended for use in the ECAT and briefly mention
alternatives. For this reason, a list is included of firms that are
commercializing kits and reagents. The book aims to contribute to
further harmonization of haemostasis assays and, ultimately, to
their standardization.
This book offers a description of current and recently developed
laboratory assays in the field of haemostasis and thrombosis. It is
the result of a unique cooperation between experts from more than
60 institutes in 12 European countries, brought together by the ECA
T (European Concerted Action on Thrombosis and Disabilities) under
the auspices of the Commission of the European Communities in
Brussels, Belgium. The ECAT, which was initiated in 1981, designed
and performed three prospective clinical studies to establish
haemostatic factors as risk indicators of thrombosis. Included were
patients with angina pectoris at risk from myocardial infarction,
patients undergoing angioplasty at risk from re-stenosis, and
patients receiving hip replacement at risk from deep venous
thrombosis. Assay procedures were chosen, training courses for
technicians held, and essential reagents were supplied from a
central source. A quality control assessment scheme served to
compare assay results both within and between laboratories. In the
angina pectoris study, centres determined most of the assays
locally; in the other two studies assays were performed centrally.
The need for further quality assessment in Europe Dr J. F. Davidson
in Glasgow, led to a separate activity coordinated by including
coagulation inhibitors and plasminogen as risk factors for familial
venous thrombosis. The Editors hope the ECA T Assay Procedures book
will contribute to further harmonization ofhaemostasis assays, and
ultimately to their standardization.
The first edition of this manual appeared in 1992 and was entitled
ECAT Assay Procedures. It was the result of a unique cooperation
between experts brought together by the European Concerted Action
on Thrombosis and Disabilities (ECAT). The Concerted Action was at
that time under the auspices of the Commission of the European
Union. The second edition, like the first edition, deals with
diagnostic tests within the field of thrombosis. However, the
second edition has a broader scope because it is no longer limited
by the frontiers of ECAT. Experts allover the world, in and outside
ECAT, have contributed to this edition. The editors are very
grateful for their contributions. The need for a new edition is
obvious. Since 1992 new assays have been introduced for research,
diagnosis, and therapy of thrombosis; for other assays improvements
have been suggested, while a few others became redundant. The
editors waived the radioimmunoassays of ~-thrombog1obulin and
platelet factor 4 due to the fact that the kits required for these
assays are rarely, or no longer, available. Also the PAI-1 activity
assay was waived as it is liable to many inconsistencies and to
large variations. A list of names and addresses of manufacturers
marketing the kits and reagents has been compiled, together with a
list of the recommended nomenclature of quantities in thrombosis
and haemostasis, in order to facilitate the use of the updated
version. These lists have been carefully compiled by Johannes J.
Sidelmann, PhD, Department of Clinical Biochemistry in Esbjerg,
Denmark.
The first edition of this manual appeared in 1992 and was entitled
ECAT Assay Procedures. It was the result of a unique cooperation
between experts brought together by the European Concerted Action
on Thrombosis and Disabilities (ECAT). The Concerted Action was at
that time under the auspices of the Commission of the European
Union. The second edition, like the first edition, deals with
diagnostic tests within the field of thrombosis. However, the
second edition has a broader scope because it is no longer limited
by the frontiers of ECAT. Experts allover the world, in and outside
ECAT, have contributed to this edition. The editors are very
grateful for their contributions. The need for a new edition is
obvious. Since 1992 new assays have been introduced for research,
diagnosis, and therapy of thrombosis; for other assays improvements
have been suggested, while a few others became redundant. The
editors waived the radioimmunoassays of ~-thrombog1obulin and
platelet factor 4 due to the fact that the kits required for these
assays are rarely, or no longer, available. Also the PAI-1 activity
assay was waived as it is liable to many inconsistencies and to
large variations. A list of names and addresses of manufacturers
marketing the kits and reagents has been compiled, together with a
list of the recommended nomenclature of quantities in thrombosis
and haemostasis, in order to facilitate the use of the updated
version. These lists have been carefully compiled by Johannes J.
Sidelmann, PhD, Department of Clinical Biochemistry in Esbjerg,
Denmark.
|
You may like...
Shakespeare and I
William McKenzie, Theodora Papadopoulou
Hardcover
R5,572
Discovery Miles 55 720
A Confession
Leo Tolstoy
Hardcover
R663
Discovery Miles 6 630
Sea Prayer
Khaled Hosseini
Hardcover
(1)
R424
R303
Discovery Miles 3 030
|