Foreword: Charles J. Pedersen (1904-1989), Nobel Laureate in Chemistry (1987) This issue is dedicated to the memory of the late Charles J. Pedersen in recognition of his outstanding contribution to scientific research, culminating in his discovery of crown ethers and their remarkable cation complexing properties and his receipt of the 1987 Nobel Prize in Chemistry. Charlie's origin and early years in Korea did not portend the creative work in chemistry which would characterize his later life. However, we can see in his early years the influence of his Norwegian father and Japanese mother who considered his formal education to be of utmost importance. At the age of eight, he was sent abroad to Japan for schooling, first at a convent school in Nagasaki, and two years later at a French-American preparatory school in Yokohama run by a Marianist order of Catholic priests and brothers. The latter group encouraged him to attend the order's University of Dayton in Ohio where he received a bachelors degree in chemical engineering. Charlie's academic experiences, his employment with du Pont, and the creative spark which he manifested at an early stage of his scientific career are detailed in the paper in this issue by Herman Schroeder. Schroeder had a long-time association with Charlie at du Pont as a co-worker, supervisor, and friend. His recollections provide insight into Charlie's creative mind. In addition, they make it clear that a long period of creative work preceded the accidental discovery of the first synthetic crown ether. It is important to note that Charlie's mind was well prepared to recognize the importance of his discovery. The field of macrocyclic chemistry, to a large degree, had its beginnings with Charlie's discovery. A first-person account of his discovery is given as the first paper in this issue. This account was prepared by him and was read at the 12th Symposium on Macrocyclic Chemistry in Hiroshima, Japan in 1987 by Herman Schroeder. The growth of this field since Charlie's first publication on the subject in 1967 has been enormous. This growth is evidenced in one segment of the field by the three-fold increase in the number of references in two Chemical Reviews articles on thermodynamic quantities associated with cation-macrocycle interaction authored by us in 1985 and 1991. Charlie lived to see much of this growth. He saw many of his own predictions of possible uses of crown ethers and related macrocycles realized. Recognition for Charlie came late in his career. He found it satisfying to see so many capable scientists go in so many directions as they applied his discovery to a wide range of chemical and other fields. He made seminal contributions to the broad area known today as molecular recognition. His work illustrates how one individual can make an enormous difference in science. The effect of his life and work on those of us who contributed papers for this issue and on many others is appreciated and is acknowledged by several of the authors in their individual papers. It is entirely appropriate to honor his memory with this special issue. R.M. Izatt, J.S. Bradshaw Department of Chemistry, Brigham Young University, Provo, UT 84602, U.S.A. Reprinted from Journal of Inclusion Phenomena and Molecular Recognition in Chemistry, Volume 12, Nos. 1-4 (1992)

This book commemorates the 25th anniversary of the International Izatt-Christensen Award in Macrocyclic and Supramolecular Chemistry. The award, one of the most prestigious of small awards in chemistry, recognizes excellence in the developing field of macrocyclic and supramolecular chemistry Macrocyclic and Supramolecular Chemistry: How Izatt-Christensen Award Winners Shaped the Field features chapters written by the award recipients who provide unique perspectives on the spectacular growth in these expanding and vibrant fields of chemistry over the past half century, and on the role of these awardees in shaping this growth. During this time there has been an upsurge of interest in the design, synthesis and characterization of increasingly more complex macrocyclic ligands and in the application of this knowledge to understanding molecular recognition processes in host-guest chemistry in ways that were scarcely envisioned decades earlier. In October 2016, Professor Jean-Pierre Sauvage and Sir J. Fraser Stoddart (author for chapter 22 "Contractile and Extensile Molecular Systems: Towards Molecular Muscles" by Jean -Pierre Sauvage, Vincent Duplan, and Frederic Niess and 20 "Serendipity" by Paul R. McGonigal and J. Fraser Stoddart respectively) were awarded the Nobel Prize in Chemistry alongside fellow Wiley author Bernard Feringa, for the design and synthesis of molecular machines.

The sustainable use of natural resources is an important global challenge, and improved metal sustainability is a crucial goal for the 21st century in order to conserve the supply of critical metals and mitigate the environmental and health issues resulting from unrecovered metals. Metal Sustainability: Global Challenges, Consequences and Prospects discusses important topics and challenges associated with sustainability in metal life cycles, from mining ore to beneficiation processes, to product manufacture, to recovery from end-of-life materials, to environmental and health concerns resulting from generated waste. The broad perspective presented highlights the global interdependence of the many stages of metal life cycles. Economic issues are emphasized and relevant environmental, health, political, industrial and societal issues are discussed. The importance of applying green chemistry principles to metal sustainability is emphasized. Topics covered include: Recycling and sustainable utilization of precious and specialty metals Formal and informal recycling from electronic and other high-tech wastes Global management of electronic wastes Metal reuse and recycling in developing countries Effects of toxic and other metal releases on the environment and human health Effect on bacteria of toxic metal release Selective recovery of platinum group metals and rare earth metals Metal sustainability from a manufacturing perspective Economic perspectives on sustainability, mineral development, and metal life cycles Closing the Loop Minerals Industry Issues The aim of this book is to improve awareness of the increasingly important role metals play in our high-tech society, the need to conserve our metal supply throughout the metal life cycle, the importance of improved metal recycling, and the effects that unhindered metal loss can have on the environment and on human health.