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Recent advances in cytotoxins and immunotoxins are accelerating our
understanding of cancer and leading to more effective therapeutic
treatments. Although a large number of articles have been published
on these cytotoxins and immunotoxins, this important information
has yet to be compiled into one comprehensive resource. For the
first time, Cytotoxins and Immunotoxins for Cancer Therapy:
Clinical Applications presents state-of-the-art information on
various cytotoxins and immunotoxins in a single, highly anticipated
publication. The editors bring together leading researchers to
summarize their work and discuss clinical trial data concerning
some of the most widely studied tumors. The book describes
Pseudomonas exotoxin (PE)-based immunotoxins and presents the
latest results from clinical trials for the treatment of recurrent
glioblastoma and other human cancers. It reviews the role of
ricin-based immunotoxins for the treatment of lymphoma, explores
several DT-based immunotoxins, and details the preclinical and
clinical development of the first FDA-approved cytotoxin. With a
focus on clinical developmental approaches to the use of cytotoxins
and immunotoxins, this book discusses exciting possibilities for
cancer therapy. It is a valuable resource for scientists,
researchers, and clinicians involved in the development of new
treatments that can help keep cancer under control, and may
ultimately lead to a cure.
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