Long-Acting Drug Delivery Systems: Pharmaceutical, Clinical, and Regulatory Aspects offers a comprehensive overview of the technical, clinical, regulatory and industrial perspectives on these drug delivery systems. The book follows a sequential order, beginning with the current technical state-of-the-field and moving on to more clinical, industrial and regulatory topics. Opening chapters describe the current needs and potential applications of implantable and long-acting therapeutic approaches. The book goes on to describe established and novel long-acting systems, with a focus on the materials used to prepare these systems and their biocompatibility. Importantly, applied topics such as scale-up manufacturing, products under clinical trials and regulatory aspects are covered, offering the reader a holistic view of this rapidly growing field.

Arthur Schopenhauer is a widely read, admired and intriguing philosopher whose ideas have had a profound impact on some of the greatest minds of the last two centuries. He is known for his powerful but simple prose-style and a philosophy that tackles everyday life. Yet even the most sympathetic and intelligent reader of his works is likely to be perplexed by seeming inconsistencies and unconventional tone of a number of his major claims.
"Schopenhauer: A Guide for the Perplexed" is a clear and thorough account of Schopenhauer's philosophy, his major works and ideas, providing an ideal guide to the important and complex thought of this key philosopher. The book explores arguments that he offers for his pessimistic worldview that have long been misunderstood. Geared towards the specific requirements of students who need to reach a sound understanding of Schopenhauer contributions to philosophy, this book also presents an in-depth analysis of his western as well as his hitherto neglected eastern sources and influences.

Bioinformatics and Computational Biology: Technological Advancements, Applications, and Opportunities is an invaluable resource for general and applied researchers who analyze biological data that is generated, at an unprecedented rate, at the global level. After careful evaluation of the requirements for current trends in bioinformatics and computational biology, it is anticipated that the book will provide an insightful resource to the academic and scientific community. Through a myriad of computational resources, algorithms, and methods, it equips readers with the confidence to both analyze biological data and estimate predictions. The book offers comprehensive coverage of the most essential and emerging topics: Cloud-based monitoring of bioinformatics multivariate data with cloud platforms Machine learning and deep learning in bioinformatics Quantum machine learning for biological applications Integrating machine learning strategies with multi-omics to augment prognosis in chronic diseases Biomedical engineering Next generation sequencing techniques and applications Computational systems biology and molecular evolution While other books may touch on some of the same issues and nuances of biological data analysis, they neglect to feature bioinformatics and computational biology exclusively, and as exhaustively. This book's abundance of several sub-topics related to almost all of the regulatory activities of biomolecules from where real data is being generated brings an added dimension.

This book offers the core conceptual base for the practice of T-Group facilitation. Drawing from the fields of psychology, social psychology, sociology, diversity studies and Indian philosophical thoughts, this book is a great resource for enhancing the practice of T-Group facilitation, for both budding and established facilitators. It covers a wide range of theories on human development, self-awareness, interpersonal interactions, groups and change. Individual and group identities, diversity, inclusion and social hierarchies are explored in detail here. The authors offer a model of T-Group facilitation based on 50 years of experience within the Indian Society for Applied Behavioural Science (ISABS). This model is useful not only for fellow practitioners of T-Groups but also for anyone engaged in facilitating groups, organizations and communities globally. This book helps one to reflect, develop and sharpen one's competencies, values and ethics in this field. The chapters are embedded with activities, quizzes, case studies and exercises to facilitate a deeper understanding of the various elements used in the book. This book will be of interest to students, teachers and practitioners of psychology, social psychology, management studies and organizational development. It will also be useful for T-Group facilitators, facilitators of experiential groups and related fields.

This book offers the core conceptual base for the practice of T-Group facilitation. Drawing from the fields of psychology, social psychology, sociology, diversity studies and Indian philosophical thoughts, this book is a great resource for enhancing the practice of T-Group facilitation, for both budding and established facilitators. It covers a wide range of theories on human development, self-awareness, interpersonal interactions, groups and change. Individual and group identities, diversity, inclusion and social hierarchies are explored in detail here. The authors offer a model of T-Group facilitation based on 50 years of experience within the Indian Society for Applied Behavioural Science (ISABS). This model is useful not only for fellow practitioners of T-Groups but also for anyone engaged in facilitating groups, organizations and communities globally. This book helps one to reflect, develop and sharpen one's competencies, values and ethics in this field. The chapters are embedded with activities, quizzes, case studies and exercises to facilitate a deeper understanding of the various elements used in the book. This book will be of interest to students, teachers and practitioners of psychology, social psychology, management studies and organizational development. It will also be useful for T-Group facilitators, facilitators of experiential groups and related fields.

A large and growing number of manufacturers are realizing the substantial financial and environmental benefits of sustainable business practices. To develop more sustainable societies, industries need to better understand how to respond to environmental, economic, and social challenges and transform industrial behavior. The objective of this book is to provide the required knowledge and accelerate the transition towards a sustainable industrial system. The book will help industries to enhance operational efficiency by reducing costs and waste. It will help them increase customer response, reach new customers, and gain competitive advantage. It offers innovation, scenario planning, and strategic analysis that goes beyond compliance, as well as case studies and remedies to the industry 4.0 challenges. Professionals, as well as students, can refer to this book to add to their knowledge on Industry 4.0 and develop new ideas and solutions to the existing and future problems.

The connections between death, contemplation and the contemplative life have been a recurrent theme in the canons of both western and eastern philosophical thought. This book examines the classical sources of this philosophical literature, in particular Plato's Phaedo and the Katha Upanishad and then proceeds to a sustained analysis and critical assessment of the sources and standpoints of a single thinker, Arthur Schopenhauer, whose work comprehensively pursues this problem. Going beyond the well examined western influences on Schopenhauer, Singh offers an in-depth account of Schopenhauer's references to eastern thought and a comprehensive examination of his eastern sources, particularly Vedanta and Buddhism. The book traces the pivotal issue of death through the whole range of Schopenhauer's writings uncovering the deeper connotations of his crucial notion of the will-to-live.

Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.

The connections between death, contemplation and the contemplative life have been a recurrent theme in the canons of both western and eastern philosophical thought. This book examines the classical sources of this philosophical literature, in particular Plato's Phaedo and the Katha Upanishad and then proceeds to a sustained analysis and critical assessment of the sources and standpoints of a single thinker, Arthur Schopenhauer, whose work comprehensively pursues this problem. Going beyond the well examined western influences on Schopenhauer, Singh offers an in-depth account of Schopenhauer's references to eastern thought and a comprehensive examination of his eastern sources, particularly Vedanta and Buddhism. The book traces the pivotal issue of death through the whole range of Schopenhauer's writings uncovering the deeper connotations of his crucial notion of the will-to-live.

The book describes hazardous waste industries, sources of waste generation, characterization and treatment processes/ methods and technique and technology to deal with the treated waste as per the prescribed standard. Advanced treatment based on the microbial remediation, plant-based decontamination, rhizoremediation and nano-based remediation is also explained. Advances in treatment technology using biotechnological tools/bionanotechnology for removal of contaminants are described. This volume will help readers to develop biotechnological and nanotechnological approaches for the remediation of hazardous waste and the developed technology that can be transferred from laboratory to land and piloting to commercial scenarios. Prof. M. H. Fulekar a Professor and Joint Director (R&D), Centre of Research for Development, Parul University. Dr. Bhawana Pathak is working as an Associate Professor and Dean in School of Environment and Sustainable Development, Central University of Gujarat.

Hydrogels are crosslinked, macromolecular polymeric materials arranged in a three-dimensional network, which can absorb and retain large amounts of water. Hydrogels are commonly used in clinical practice and experimental medicine for a wide range of applications, including drug delivery, tissue engineering and regenerative medicine, diagnostics, cellular immobilization, separation of biomolecules or cells, and barrier materials to regulate biological adhesions. This book elucidates the underlying concepts and emerging applications of hydrogels and will provide key case studies and critical analysis of the existing research.

The vibration of Heat Exchange Tubes due to hydrodynamic fluid coupling is an international problem for Nuclear fuel assemblies etc. on account of frequent failure of Heat exchanger tube, which causes not only expensive repair but a great loss to the plant. Thus, several studies in this field have been made so far. But here, a study of three circular cylindrical tubes in a liquid is done on the analytical approach. The author also describes the various parameters for maximum efficiency of heat transmission from Heat Exchanger's, which is defined as; nH =F (G/R, V) = Heat transmission efficiency of the heat exchanger, where G=gap between two adjoining tubes, R= Radius of cylindrical tubes (if considered of same diameters) and V= fluid flow velocity and geometry of tubes. The relations amongst the above parameters are yet to derive to solve this problem.